Babakova L L, Pozdniakov O M
Biull Eksp Biol Med. 1986 Jan;101(1):98-102.
The ultrastructural analysis of the muscle biopsy samples from patients with different neuro-muscular diseases revealed; both degeneration and regeneration of the muscle fibres. The number of satellite cells was increased due to their division and myonuclear segregation. Activated satellite cells were converted into myoblasts which probably could replace the injured fragments of the muscle fibres or form the myotubes. The process of muscle fibre regeneration is restricted not only by the damage of the muscle itself, but by the dystrophic process affecting satellite cells.
肌纤维出现了变性和再生。卫星细胞数量因分裂和肌核分离而增加。活化的卫星细胞转化为成肌细胞,这些成肌细胞可能会替代受损的肌纤维片段或形成肌管。肌纤维再生过程不仅受肌肉自身损伤的限制,还受影响卫星细胞的营养不良过程的限制。