Pérez-Clausell J, Danscher G
Brain Res. 1986 Jan 8;362(2):358-61. doi: 10.1016/0006-8993(86)90463-4.
The fate of sulphide-bound zinc was studied in synaptic boutons of the telencephalon after intracerebral injection of sodium sulphide. After short survival times (30 min), zinc was found in boutons located in synaptic vesicles, later in vesicles and in the synaptic clefts, and at long survival times (48 h) zinc was located solely in the extracellular space. The present data suggest that: zinc, when bound to sulphide, is released into the synaptic cleft in a time dependent way; and different zinc-containing boutons have different turnover periods, the hippocampal giant mossy fiber boutons being the tardiest to empty their zinc sulphide content.
在脑内注射硫化钠后，研究了端脑突触小体中硫化物结合锌的命运。在短存活时间（30分钟）后，锌出现在位于突触小泡中的突触小体中，随后出现在小泡和突触间隙中，而在长存活时间（48小时）时，锌仅位于细胞外空间。目前的数据表明：当锌与硫化物结合时，它会以时间依赖性方式释放到突触间隙中；并且不同含锌的突触小体有不同的周转期，海马大苔藓纤维突触小体排空其硫化锌含量的速度最慢。
