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数字之外:肥胖对女性产科肛门括约肌损伤(OASI)结局的影响

Beyond the numbers: Impact of obesity on obstetric anal sphincter injury (OASI) outcomes in women.

作者信息

Rotem Reut, Galvin Daniel, McCormack Kate, O'Sullivan Orfhlaith E, Hayes-Ryan Deirdre

机构信息

Department of Urogynecology, Cork University Maternity Hospital, Cork, Ireland.

Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Affiliated with the Hebrew University School of Medicine, Jerusalem, Israel.

出版信息

Int J Gynaecol Obstet. 2025 Mar;168(3):1171-1177. doi: 10.1002/ijgo.15981. Epub 2024 Oct 21.

Abstract

OBJECTIVE

To compare the risk profiles, anatomical, and functional outcomes between obese and non-obese women who experienced obstetric anal sphincter injury (OASI).

METHODS

A retrospective electronic database study was conducted at Cork University Maternity Hospital (CUMH). Women with missing data/repairs conducted outside CUMH were excluded. Participants were categorized into obese (BMI ≥30 kg/m) and non-obese (BMI <30 kg/m) groups. Primary measure was a composite adverse outcome assessed 6 months post-delivery, including one or more of the following: resting pressure <40 mmHg, squeezing pressure <100 mmHg, defects in the internal and/or external anal sphincter. Statistical analyses were performed using SPSS version 28.

RESULTS

Among the 349 women included in the study, 285 (81.7%) had a BMI <30 kg/m and 64 (18.3%) had a BMI ≥30 kg/m. Gestational diabetes was significantly higher in obese women. No significant differences were observed in newborn weight or mode of delivery. The majority of tears were classified as grade 3B in both groups. Attendance rates at the OASI clinic did not differ between the groups. Among those attending, no statistical differences were noted in manometry results, which were reduced in both groups. Rates of internal anal sphincter defects were lower in the obese group (7.0% vs 15.6%, P = 0.15) and external anal sphincter defects were significantly lower in obese women (0% vs 9.1%, P = 0.04). No difference was found in the rates of composite adverse outcomes between the groups.

CONCLUSION

Functional outcomes and manometry results did not differ, but non-obese women had higher rates of anatomical defects in OASI, requiring further study.

摘要

目的

比较发生产科肛门括约肌损伤(OASI)的肥胖和非肥胖女性的风险特征、解剖学及功能结局。

方法

在科克大学妇产医院(CUMH)进行了一项回顾性电子数据库研究。排除在CUMH以外进行数据缺失/修补的女性。参与者被分为肥胖(BMI≥30 kg/m)和非肥胖(BMI<30 kg/m)组。主要测量指标是产后6个月评估的综合不良结局,包括以下一项或多项:静息压力<40 mmHg、挤压压力<100 mmHg、内括约肌和/或外括约肌缺陷。使用SPSS 28版进行统计分析。

结果

纳入研究的349名女性中,285名(81.7%)BMI<30 kg/m,64名(18.3%)BMI≥30 kg/m。肥胖女性的妊娠期糖尿病显著更高。新生儿体重或分娩方式未观察到显著差异。两组中大多数撕裂伤被分类为3B级。OASI门诊的就诊率在两组之间没有差异。在就诊者中,测压结果没有统计学差异,两组均降低。肥胖组的内括约肌缺陷率较低(7.0%对15.6%,P=0.15),肥胖女性的外括约肌缺陷率显著较低(0%对9.1%,P=0.04)。两组之间的综合不良结局发生率没有差异。

结论

功能结局和测压结果没有差异,但非肥胖女性在OASI中的解剖学缺陷率更高,需要进一步研究。

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本文引用的文献

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Obesity in pregnancy: a comparison of four national guidelines.孕期肥胖:四项国家指南的比较
J Matern Fetal Neonatal Med. 2019 Aug;32(15):2580-2590. doi: 10.1080/14767058.2018.1440546. Epub 2018 Feb 26.

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