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寻常型银屑病样狼疮:一项诊断挑战。

Psoriasiform Lupus Vulgaris: A Diagnostic Challenge.

作者信息

Liyanage Achala, Bandara Manuji, Liyanage Thusharie

机构信息

Faculty of Medicine, University of Ruhuna, Galle, LKA.

出版信息

Cureus. 2024 Sep 19;16(9):e69722. doi: 10.7759/cureus.69722. eCollection 2024 Sep.

DOI:10.7759/cureus.69722
PMID:39429290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11490278/
Abstract

Cutaneous tuberculosis is a rare and often overlooked manifestation of tuberculosis, frequently leading to delays from onset to diagnosis. This case report describes the presentation of a 65-year-old male with an asymptomatic solitary plaque with silvery scales persisting for over five years, mimicking solitary plaque psoriasis. Despite intermittent treatment with a potent steroid and a combination of calcipotriol, the patient had only modest alleviation. A skin biopsy was performed, and the histology revealed caseating tuberculoid granulomas. Following treatment with an antituberculosis regimen, the lesion showed significant improvement. The case report highlights the diagnostic challenges of this uncommon entity and the importance of thorough evaluation of recurrent and persistent lesions, particularly in populations with a higher prevalence of tuberculosis. Further, it aims to provide valuable insight to healthcare providers on the atypical clinical presentations of lupus vulgaris mimicking common dermatoses.

摘要

皮肤结核是一种罕见且常被忽视的结核病表现形式,常常导致从发病到诊断的延迟。本病例报告描述了一名65岁男性,其有无症状的孤立性斑块,伴有银色鳞屑,持续五年多,酷似孤立性斑块状银屑病。尽管使用强效类固醇和卡泊三醇联合进行了间歇性治疗,但患者仅略有缓解。进行了皮肤活检,组织学检查显示为干酪样结核样肉芽肿。在接受抗结核治疗后,病变有显著改善。该病例报告强调了这种罕见疾病的诊断挑战,以及对复发性和持续性病变进行全面评估的重要性,特别是在结核病患病率较高的人群中。此外,它旨在为医疗服务提供者提供关于寻常狼疮模仿常见皮肤病的非典型临床表现的宝贵见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c25/11490278/c3c14a99724e/cureus-0016-00000069722-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c25/11490278/18585525be66/cureus-0016-00000069722-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c25/11490278/65451f5b57de/cureus-0016-00000069722-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c25/11490278/0aefba0ab5c1/cureus-0016-00000069722-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c25/11490278/b623d1ca952c/cureus-0016-00000069722-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c25/11490278/d24093704c40/cureus-0016-00000069722-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c25/11490278/c3c14a99724e/cureus-0016-00000069722-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c25/11490278/18585525be66/cureus-0016-00000069722-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c25/11490278/65451f5b57de/cureus-0016-00000069722-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c25/11490278/0aefba0ab5c1/cureus-0016-00000069722-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c25/11490278/b623d1ca952c/cureus-0016-00000069722-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c25/11490278/d24093704c40/cureus-0016-00000069722-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c25/11490278/c3c14a99724e/cureus-0016-00000069722-i06.jpg

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本文引用的文献

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Cureus. 2023 Jun 16;15(6):e40495. doi: 10.7759/cureus.40495. eCollection 2023 Jun.
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