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2000 - 2020年美国50岁及以上成年人慢性阻塞性肺疾病的患病率和发病率趋势

Trends in the prevalence and incidence of chronic obstructive pulmonary disease among adults aged ≥50 years in the United States, 2000-2020.

作者信息

Meng Yaxian, Ji Qianqian, Zhang Aijie, Zhan Yiqiang

机构信息

Department of Epidemiology, School of Public Health (Shenzhen) Sun Yat-Sen University Shenzhen Guangdong China.

Unit of Integrative Epidemiology, Institute of Environmental Medicine Karolinska Institutet Stockholm Sweden.

出版信息

Chronic Dis Transl Med. 2024 May 31;10(4):302-311. doi: 10.1002/cdt3.135. eCollection 2024 Dec.

Abstract

BACKGROUND

Understanding the trends of the prevalence and incidence rate of chronic obstructive pulmonary disease (COPD) is vital for improving the control and prevention of COPD. We aimed to examine the trends in the prevalence and incidence rate of COPD among adults aged 50 years or older in the United States during 2000-2020.

METHODS

Utilizing data from the Health and Retirement Study, we analyzed COPD prevalence across survey waves and calculated COPD incidence rates between consecutive interview waves, stratified by gender and race. We employed joinpoint regression models to investigate trends in COPD prevalence and incidence.

RESULTS

The individuals reporting COPD are more likely to be women and Caucasians. The age-adjusted prevalence of COPD among adults aged 50 years and over showed an increasing trend throughout the study period, spanning from 9.02% in 2000 to 9.88% in 2020 (average biennial percent change [ABPC] = 0.41, 95% confidence interval [CI]: 0.10, 0.71;  = 0.01). The age-adjusted incidence rate of COPD among adults aged 50 and over showed a decreasing trend throughout the study period 1031.1 per 100,000 person-years in 2000 to 700.5 per 100,000 person-years in 2020 (ABPC = -1.63, 95% CI: -2.88, -0.36;  = 0.02).

CONCLUSION

Our findings indicate a rising prevalence of COPD among older adults in the United States since 2000, while the incidence rate of COPD has shown a declining trend.

摘要

背景

了解慢性阻塞性肺疾病(COPD)的患病率和发病率趋势对于改善COPD的控制和预防至关重要。我们旨在研究2000年至2020年期间美国50岁及以上成年人中COPD的患病率和发病率趋势。

方法

利用健康与退休研究的数据,我们分析了各调查波次的COPD患病率,并计算了连续访谈波次之间的COPD发病率,按性别和种族分层。我们采用连接点回归模型来研究COPD患病率和发病率的趋势。

结果

报告患有COPD的个体更可能是女性和白种人。在整个研究期间,50岁及以上成年人中经年龄调整的COPD患病率呈上升趋势,从2000年的9.02%上升至2020年的9.88%(平均两年期百分比变化[ABPC]=0.41,95%置信区间[CI]:0.10,0.71;P=0.01)。在整个研究期间,50岁及以上成年人中经年龄调整的COPD发病率呈下降趋势,从2000年的每10万人年1031.1例降至2020年的每10万人年700.5例(ABPC=-1.63,95%CI:-2.88,-0.36;P=0.02)。

结论

我们的研究结果表明,自2000年以来,美国老年人中COPD的患病率呈上升趋势,而COPD的发病率呈下降趋势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3b6/11483547/c6b116a929ce/CDT3-10-302-g002.jpg

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