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准分子激光原位角膜磨镶术(LASIK)24年后迟发性外伤性角膜瓣脱位及继发性上皮内生

Late-onset traumatic corneal flap dislocation and secondary epithelial ingrowth 24 years after LASIK.

作者信息

Zhang Xu, Wang Huixian, Gao Xiaowei, Li Wenjing

机构信息

Ophthalmology Department, Xinjiang 474 Hospital, Urumqi, 830011, Xinjiang Autonomous Region, China.

出版信息

Am J Ophthalmol Case Rep. 2024 Oct 4;36:102180. doi: 10.1016/j.ajoc.2024.102180. eCollection 2024 Dec.

DOI:10.1016/j.ajoc.2024.102180
PMID:39429624
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11490701/
Abstract

PURPOSE

To analyze the diagnostic process, treatment, and post-operative outcomes of a unique case involving a late-onset (24 years post) traumatic corneal flap displacement after Laser-assisted in situ keratomileusis (LASIK) surgery due to a plant-related trauma. with an emphasis on the accompanying extensive epithelial ingrowth beneath the flap.

OBSERVATIONS

A 59-year-old male patient experienced corneal flap displacement 24 years post-LASIK due to a minor plant-related trauma. This case was complicated by extensive epithelial ingrowth beneath the flap, which was initially misdiagnosed with fungal keratitis. Upon identification of the actual cause, corneal flap repair surgery was performed, leading to partial vision recovery.

CONCLUSIONS AND IMPORTANCE

This case signifies the potential for LASIK flap displacement even decades post-surgery due to minor traumas and highlights the need for vigilance in diagnosing associated complications like epithelial ingrowth. It indicates the importance of ophthalmologists and clinicians being vigilant for such complications and necessitates their familiarity with basic management techniques or quick referral to a corneal refractive surgery specialist. This report of a 24-year interval between LASIK and traumatic flap displacement with epithelial ingrowth is one of the longest known. The case also demonstrates that patients with late flap displacement can regain significant visual acuity with timely and appropriate management.

摘要

目的

分析一例独特病例的诊断过程、治疗及术后结果。该病例为激光原位角膜磨镶术(LASIK)术后24年因植物相关创伤导致迟发性角膜瓣移位,并着重关注瓣下伴随的广泛上皮内生情况。

观察结果

一名59岁男性患者在LASIK术后24年因轻微植物相关创伤发生角膜瓣移位。该病例因瓣下广泛上皮内生而复杂化,最初被误诊为真菌性角膜炎。在确定实际病因后,进行了角膜瓣修复手术,视力部分恢复。

结论与重要性

该病例表明,即使在手术后数十年,轻微创伤也可能导致LASIK角膜瓣移位,并凸显了警惕上皮内生等相关并发症诊断的必要性。这表明眼科医生和临床医生对这类并发症保持警惕的重要性,并且需要他们熟悉基本的处理技术或迅速转诊至角膜屈光手术专家。该报告中LASIK与创伤性瓣移位及上皮内生之间间隔24年,是已知最长的间隔之一。该病例还表明,迟发性瓣移位患者通过及时适当的处理可恢复显著视力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d0c/11490701/e597a14fd6ef/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d0c/11490701/c661ff88776b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d0c/11490701/8a30f723e88c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d0c/11490701/e597a14fd6ef/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d0c/11490701/c661ff88776b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d0c/11490701/8a30f723e88c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d0c/11490701/e597a14fd6ef/gr3.jpg

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本文引用的文献

1
Efficacy and Safety of Surgically Managed Late Traumatic LASIK Flap Displacements in a Study of 66 Cases.
J Refract Surg. 2022 Apr;38(4):270-276. doi: 10.3928/1081597X-20220128-01. Epub 2022 Apr 1.
2
Traumatic Flap Complications After Femtosecond LASIK.飞秒 LASIK 术后的瓣相关并发症。
Cornea. 2022 May 1;41(5):604-608. doi: 10.1097/ICO.0000000000002782.
3
Management of late traumatic LASIK flap dislocation related to dog scratch 16 Years postoperatively.术后16年因狗抓伤导致的晚期外伤性准分子激光原位角膜磨镶术(LASIK)瓣脱位的处理
Am J Ophthalmol Case Rep. 2022 Jan 28;25:101270. doi: 10.1016/j.ajoc.2022.101270. eCollection 2022 Mar.
4
Flap amputation for long-standing post-LASIK flap dislocation with epithelial ingrowth.LASIK 术后长期瓣脱位伴上皮内生长的瓣切除术。
BMJ Case Rep. 2022 Feb 8;15(2):e247068. doi: 10.1136/bcr-2021-247068.
5
Incidence, Risk, and Visual Outcomes after Repositioning of Acute Non-Traumatic Flap Dislocations Following Femtosecond-Assisted LASIK.飞秒激光制瓣准分子原位角膜磨镶术后急性非创伤性瓣脱位复位后的发生率、风险及视觉预后
J Clin Med. 2021 Jun 3;10(11):2478. doi: 10.3390/jcm10112478.
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Complications of laser-assisted keratomileusis.激光辅助角膜磨镶术的并发症。
Indian J Ophthalmol. 2021 Jul;69(7):1658-1669. doi: 10.4103/ijo.IJO_1872_20.
7
Application of two-part glue technique in epithelial ingrowth after laser keratomileusis flap dislocation.两部分胶水技术在准分子激光原位角膜磨镶术瓣脱位后上皮内生中的应用。
Indian J Ophthalmol. 2021 Jun;69(6):1614-1617. doi: 10.4103/ijo.IJO_3263_20.
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Traumatic displacement of laser in situ keratomileusis flaps: an integrated clinical case presentation.准分子原位角膜磨镶术(LASIK)瓣的外伤性移位:综合临床病例报告
BMC Ophthalmol. 2021 Apr 13;21(1):177. doi: 10.1186/s12886-021-01938-y.
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Traumatic laser in situ keratomileusis flap dislocation with epithelial ingrowth, Propionibacterium acnes infection, and diffuse lamellar keratitis: A case report.伴有上皮内生、痤疮丙酸杆菌感染及弥漫性板层角膜炎的创伤性准分子原位角膜磨镶术瓣脱位:1例报告
Medicine (Baltimore). 2020 Mar;99(10):e19257. doi: 10.1097/MD.0000000000019257.
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