Yamashina M, Kobara T Y
Cancer. 1986 Jan 15;57(2):340-5. doi: 10.1002/1097-0142(19860115)57:2<340::aid-cncr2820570225>3.0.co;2-z.
A case of squamous cell carcinoma of the endometrium in a 72-year-old woman is presented. A review of the previous 28 cases of endometrial squamous cell carcinoma (ESCC) that are adequately substantiated in the literature revealed several misconceptions about this rare tumor: the association with pyometra is not as frequent; the lesion does occur in premenopausal women; squamous metaplasia of the endometrium is not always coexistent; and malignant transformation of squamous metaplasia to ESCC has never been convincingly demonstrated. In the current case, a focal sarcomatoid spindle-cell tumor was associated with typical ESCC; however, light and electron microscopic examinations provided convincing evidence that the tumor was composed solely of ESCC. Ultrastructure of the spindle-cell tumor revealed it to be essentially identical to that of a spindle-cell variant of squamous cell carcinoma reported previously.
本文报告了一例72岁女性子宫内膜鳞状细胞癌病例。回顾文献中充分证实的既往28例子宫内膜鳞状细胞癌（ESCC）病例发现，对于这种罕见肿瘤存在一些误解：与积脓的关联并不常见；该病变确实发生在绝经前女性中；子宫内膜鳞状化生并非总是并存；并且从未令人信服地证明过鳞状化生向ESCC的恶性转化。在当前病例中，一个局灶性肉瘤样梭形细胞瘤与典型的ESCC相关；然而，光镜和电镜检查提供了令人信服的证据，表明该肿瘤仅由ESCC组成。梭形细胞瘤的超微结构显示其与先前报道的鳞状细胞癌梭形细胞变体基本相同。
