Hopkin I D, Harlow R A, Stevens P J
Br J Cancer. 1970 Mar;24(1):71-6. doi: 10.1038/bjc.1970.10.
A case of primary squamous carcinoma of the body of the uterus in an 83 year old patient is reported. It is believed to be only the fourteenth adequately substantiated example. This condition apparently occurs at a average age of 5 or more years greater than that at which adenocarcinoma of the endometrium occurs. Our patient may have had generalized squamous metaplasia of the uterine surface epithelium preceding development of this tumour, but the aetiologh of the squamous metaplasia in this case is not clear. One possible factor was her menopause by irradiation 35 years before the tumour developed; an association between irradiation and uterine malignancy is reported but the significance of that association is not certain.
报告了一例83岁患者的原发性子宫体鳞状细胞癌。据信这仅是第14例有充分证据的病例。这种情况显然发生的平均年龄比子宫内膜腺癌发生的平均年龄大5岁或更多。我们的患者在该肿瘤发生之前子宫表面上皮可能已经发生了广泛性鳞状化生，但该病例中鳞状化生的病因尚不清楚。一个可能的因素是在肿瘤发生前35年她因放疗而绝经；有报道称放疗与子宫恶性肿瘤之间存在关联，但这种关联的意义尚不确定。
