Wilking N, Petrelli N J, Herrera-Ornelas L, Walsh D, Mittelman A
Cancer. 1986 Feb 1;57(3):669-71. doi: 10.1002/1097-0142(19860201)57:3<669::aid-cncr2820570345>3.0.co;2-w.
A comparison of the rigid with the flexible sigmoidoscope was evaluated in 293 patients as part of a screening project for colorectal cancer at Roswell Park Memorial Institute. Patients with either a positive family history for colorectal cancer, a positive stool guaiac test result, a history of hematochezia, or a change in bowel habits were randomly assigned to either rigid or flexible sigmoidoscopy. The median distance of colon examined with the flexible instrument was significantly greater than with the rigid scope (55 versus 17 cm, respectively). A significantly greater number of malignant and premalignant lesions were found with the flexible instrument than with the rigid scope. It was concluded that the flexible sigmoidoscope is superior to the rigid scope in the process of screening for colorectal lesions.
作为罗斯韦尔公园纪念研究所结直肠癌筛查项目的一部分，对293例患者进行了硬式乙状结肠镜与软式乙状结肠镜的比较评估。有结直肠癌家族史阳性、大便隐血试验结果阳性、便血史或排便习惯改变的患者被随机分配接受硬式或软式乙状结肠镜检查。使用软式器械检查的结肠中位距离明显大于硬式乙状结肠镜（分别为55厘米和17厘米）。与硬式乙状结肠镜相比，软式器械发现的恶性和癌前病变数量明显更多。得出的结论是，在结直肠病变筛查过程中，软式乙状结肠镜优于硬式乙状结肠镜。
