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Neuromodulation for Apathy in Alzheimer's Disease: A Double-Blind, Randomized, Sham-Controlled Pilot Study.阿尔茨海默病患者淡漠的神经调节治疗:一项双盲、随机、假刺激对照的初步研究。
J Alzheimers Dis. 2020;77(4):1483-1493. doi: 10.3233/JAD-200640.
2
Sensory Stimulation for Nursing-Home Residents: Systematic Review and Meta-Analysis of Its Effects on Sleep Quality and Rest-Activity Rhythm in Dementia.疗养院居民的感觉刺激:对其在痴呆症中对睡眠质量和活动-休息节律影响的系统评价和荟萃分析。
Dement Geriatr Cogn Disord. 2020;49(3):219-234. doi: 10.1159/000509433. Epub 2020 Sep 11.
3
Historic concepts of dementia and Alzheimer's disease: From ancient times to the present.痴呆和阿尔茨海默病的历史概念:从古至今。
Rev Neurol (Paris). 2020 Mar;176(3):140-147. doi: 10.1016/j.neurol.2019.03.004. Epub 2019 Jun 4.
4
Sensory-Based Interventions for Adults with Dementia and Alzheimer's Disease: A Scoping Review.针对患有痴呆症和阿尔茨海默病的成年人的基于感觉的干预措施:一项范围综述
Occup Ther Health Care. 2020 Jul;34(3):171-201. doi: 10.1080/07380577.2019.1608488. Epub 2019 May 8.
5
Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition.多感官伽马刺激可改善阿尔茨海默病相关病理并改善认知。
Cell. 2019 Apr 4;177(2):256-271.e22. doi: 10.1016/j.cell.2019.02.014. Epub 2019 Mar 14.
6
Why Do They Just Sit? Apathy as a Core Symptom of Alzheimer Disease.他们为什么只是坐着?冷漠是阿尔茨海默病的核心症状。
Am J Geriatr Psychiatry. 2019 Apr;27(4):395-405. doi: 10.1016/j.jagp.2018.12.013. Epub 2018 Dec 17.
7
Symptoms of apathy and passivity in dementia: A simultaneous concept analysis.痴呆症中冷漠和被动症状:同步概念分析。
J Clin Nurs. 2019 Feb;28(3-4):410-419. doi: 10.1111/jocn.14663. Epub 2018 Sep 24.
8
Apathy: Risk Factor for Mortality in Nursing Home Patients.冷漠:养老院患者死亡的风险因素。
J Am Geriatr Soc. 2017 Oct;65(10):2182-2189. doi: 10.1111/jgs.15007. Epub 2017 Aug 9.
9
[MEASURING THE EFFECT OF MULTI-SENSORY STIMULATION IN THE SNOEZELEN ROOM ON SLEEP QUALITY OF ALZHEIMER PATIENTS USING ACTIGRAPH].[使用活动记录仪测量多感官刺激在思乐康房对阿尔茨海默病患者睡眠质量的影响]
Harefuah. 2016 Dec;155(12):727-730.
10
Efficacy of Antidepressants for Depression in Alzheimer's Disease: Systematic Review and Meta-Analysis.抗抑郁药治疗阿尔茨海默病抑郁的疗效:系统评价与荟萃分析
J Alzheimers Dis. 2017;58(3):725-733. doi: 10.3233/JAD-161247.

多感官刺激对老年阿尔茨海默病患者淡漠症状的影响

Effects of Multi-Sensory Stimulation on Apathy Symptoms in Elderly Patients with Alzheimer's Disease.

作者信息

Li Yang, Zhao Teng, Wang Yu, Yang Xuewen, Lv Yinghui, Li Shumei, Yang Xiujun, Li Li

机构信息

Department of Medical Examination, the Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China.

Department of Intensive Care Medicine, the Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China.

出版信息

Iran J Public Health. 2024 Jun;53(6):1343-1351.

PMID:39430139
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11488543/
Abstract

BACKGROUND

We aimed to explore the effect of multi-sensory stimulation on apathy symptoms in elderly patients with Alzheimer's disease (AD).

METHODS

Eighty elderly patients with AD admitted to the Third Affiliated Hospital of Qiqihar Medical University, China from January 2022 to February 2023 were selected as the research objects by convenient sampling method. According to the random number table, they were divided into intervention group and control group, with 40 cases in each group. The control group was given routine nursing, while the intervention group was given multi-sensory stimulation based on this nursing. Apathy evaluation scale (AES), Behavioral pathology in Alzheimer's disease rating scale (BEHAVE-AD) and Quality of Life Scale for dementia patients (QoL-AD) were used to compare the results.

RESULTS

Compared with the control group, the scores of AES and BEHAVE-AD in intervention group were lower ( was -7.312 and 11.88 respectively, < 0.05), and the scores of QoL-AD in intervention group were significantly higher than those in control group were ( was -15.311, < 0.01).

CONCLUSION

Multi-sensory stimulation can relieve apathy symptoms, mental and behavioral symptoms and improve the quality of life of elderly patients with AD, which is worth popularizing in clinical practice.

摘要

背景

我们旨在探讨多感官刺激对老年阿尔茨海默病(AD)患者冷漠症状的影响。

方法

采用便利抽样法,选取2022年1月至2023年2月在中国齐齐哈尔医学院附属第三医院收治的80例老年AD患者作为研究对象。根据随机数字表,将其分为干预组和对照组,每组40例。对照组给予常规护理,干预组在此基础上给予多感官刺激。采用冷漠评估量表(AES)、阿尔茨海默病行为病理评定量表(BEHAVE-AD)和痴呆患者生活质量量表(QoL-AD)比较结果。

结果

与对照组相比,干预组的AES和BEHAVE-AD评分较低(分别为-7.312和11.88,P<0.05),干预组的QoL-AD评分显著高于对照组(为-15.311,P<0.01)。

结论

多感官刺激可缓解老年AD患者的冷漠症状、精神和行为症状,提高其生活质量,值得在临床实践中推广。