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Neurotoxicology. 2021 Sep;86:52-58. doi: 10.1016/j.neuro.2021.06.005. Epub 2021 Jun 30.
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Incidence, risk factors, prognosis, and health-related quality of life after stroke in a low-resource community in Chile (ÑANDU): a prospective population-based study.智利低资源社区卒中的发生率、风险因素、预后和与健康相关的生活质量(ÑANDU):一项基于人群的前瞻性研究。
Lancet Glob Health. 2021 Mar;9(3):e340-e351. doi: 10.1016/S2214-109X(20)30470-8. Epub 2021 Jan 7.
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Smoking and Quality of Life - Is there really an association? Evidence from a Nepalese sample.吸烟与生活质量——真的存在关联吗?来自尼泊尔样本的证据。
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Global, regional, and national burden of stroke, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.全球、区域和国家卒中负担,1990-2016 年:2016 年全球疾病负担研究的系统分析。
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与新发急性缺血性脑卒中患者生活质量相关的因素:一项基于社区的病例对照研究。

Factors associated with quality of life among newly diagnosed acute ischemic stroke patients: a community-based case-control study.

机构信息

Community Health, Faculty of Public Health, Kasetsart University, Muang, Sakonnakhon, Thailand.

Sakon Nakhon Provincial Hospital, Sakhonnakhon, Thailand.

出版信息

PeerJ. 2024 Oct 16;12:e18266. doi: 10.7717/peerj.18266. eCollection 2024.

DOI:10.7717/peerj.18266
PMID:39430556
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11490225/
Abstract

BACKGROUND

Stroke burden is expected to increase and surviving a bout of stroke may leave one with a chronic or disabling outcome decreasing significantly the quality of life of the sufferer. The study aimed to explore the association between quality of life (QoL) in stroke and non-stroke individuals in a predominantly agricultural community.

METHOD

A community-based case-control study was conducted among 154 cases aged 18 and 75 diagnosed with incident stroke. Controls were 554 non-stroke individuals ( = 554) recruited from a community where cases resided. Cases and controls were matched for age, gender and residential area. Using a self-reported questionnaire of the World Health Organization Quality of Life (WHOQOL-BREF), socio-demographic characteristics and lifestyle habits were measured in association with QoL. Statistical analyses included multivariable logistic regression models, adjusted odds ratio (aOR) and 95% confidence interval (CI).

RESULTS

Significant predictors associated with low-medium QoL were having a larger waist circumference (aOR = 1.619, 95%CI [1.003-2.612]) and being a farmer (aOR = 2.976, 95%CI [1.143-7.750]) but having a current smoking habit and being male were at lesser odds with low-medium QoL (aOR = 0.381, 95%CI [0.191-0.757]) and (aOR = 0.564, 95%CI [0.323-0.985]) respectively. In all domains, women were at a higher risk of low-medium QoL while in physical health and environment domains, it was having a larger waist circumference. In both physical health and psychological domains, being married was protective to low-medium QoL so also being age 39 or younger and having a higher education in social relationship domain.

CONCLUSION

Waist circumference, occupation, smoking habit and gender are associated with low-medium QoL. Addressing the influence of such factors could create an additional therapeutic line in the primary prevention of stroke in at-risk populations.

摘要

背景

预计中风负担将会增加,中风幸存患者可能会留下慢性或致残的后果,大大降低患者的生活质量。本研究旨在探索在以农业为主的社区中,中风患者和非中风患者的生活质量(QoL)之间的关联。

方法

在一个社区中进行了一项基于社区的病例对照研究,该社区有 154 名年龄在 18 至 75 岁之间的初发性中风患者被诊断为病例。对照组为 554 名非中风个体(n=554),从病例居住的社区中招募。病例和对照组按年龄、性别和居住区域进行匹配。使用世界卫生组织生活质量问卷(WHOQOL-BREF)的自我报告问卷,测量社会人口统计学特征和生活方式习惯与生活质量的关系。统计分析包括多变量逻辑回归模型、调整后的优势比(aOR)和 95%置信区间(CI)。

结果

与低-中生活质量相关的显著预测因素包括腰围较大(aOR=1.619,95%CI [1.003-2.612])和农民职业(aOR=2.976,95%CI [1.143-7.750]),但有吸烟习惯和男性则不太可能出现低-中生活质量(aOR=0.381,95%CI [0.191-0.757])和(aOR=0.564,95%CI [0.323-0.985])。在所有领域,女性都有更高的低-中生活质量风险,而在生理健康和环境领域,腰围较大则是一个风险因素。在生理健康和心理领域,已婚状态对低-中生活质量有保护作用,而年龄在 39 岁或以下以及社会关系领域的较高教育程度也是如此。

结论

腰围、职业、吸烟习惯和性别与低-中生活质量相关。解决这些因素的影响可能会为高危人群中风的一级预防提供额外的治疗途径。