Terabe Yuta
Limb Salvage Center, Kasukabe Chuo General Hospital, 344-0063 midori5-9-4, Kasukabe, Saitama, Japan.
JPRAS Open. 2024 Sep 14;42:213-216. doi: 10.1016/j.jpra.2024.09.009. eCollection 2024 Dec.
Patients with chronic limb-threatening ischemia experience long-duration pain during ulcer treatment. Hence, painkillers are gradually increased, but adverse events often occur. Spinal cord stimulation trial is one of the methods used to manage such pain.
The study was performed at the Limb Salvage Center in Kasukabe Chuo General Hospital. Total 41 patients with mean age 70.4 ± 9.58 years underwent spinal cord stimulation trial for 2 weeks. Among them, 33 (80 %) were male, and 8 (20 %) were female. Numerical rating scores, wound results, spinal cord stimulation-related adverse events, and total dose of oral painkillers were evaluated.
Postoperatively, itching and bleeding were reported. The numerical rating scores improved from 7/10 before to 2/10 at 2 days after the spinal cord stimulation ( 0.001). The total doses of oral painkillers showed no change before and after spinal cord stimulation ( 0.05).
Spinal cord stimulation is recommended for peripheral artery disease because it can improve numerical rating scores for a short term. Therefore, this trial approach can sufficiently control pain against chronic limb-threatening ischemia, without undergoing implantation.
慢性肢体威胁性缺血患者在溃疡治疗期间会经历长时间疼痛。因此,止痛药用量逐渐增加,但不良事件经常发生。脊髓刺激试验是用于处理此类疼痛的方法之一。
该研究在春日部中央综合医院肢体挽救中心进行。共有41例平均年龄为70.4±9.58岁的患者接受了为期2周的脊髓刺激试验。其中,33例(80%)为男性,8例(20%)为女性。评估了数字评分、伤口结果、脊髓刺激相关不良事件以及口服止痛药的总剂量。
术后报告有瘙痒和出血情况。数字评分从脊髓刺激前的7/10改善至刺激后2天的2/10(P<0.001)。脊髓刺激前后口服止痛药总剂量无变化(P>0.05)。
对于外周动脉疾病,推荐采用脊髓刺激,因为它能在短期内改善数字评分。因此,这种试验方法可以充分控制慢性肢体威胁性缺血引起的疼痛,而无需进行植入。