Zhu Yangguang, Ye Chen, Xiao Xiao, Sun Zhuang, Li Xiufen, Fu Li, Karimi-Maleh Hassan, Chen Jun, Lin Cheng-Te
Key Laboratory of Advanced Marine Materials, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, P. R. China.
Laboratory of Environmental Biotechnology, School of Environmental and Civil Engineering, Jiangnan University, Wuxi 214122, P. R. China.
Mater Horiz. 2025 Jan 20;12(2):343-363. doi: 10.1039/d4mh00776j.
Owing to the extensive use of antibiotics for treating infectious diseases in livestock and humans, the resulting residual antibiotics are a burden to the ecosystem and human health. Hence, for human health and ecological safety, it is critical to determine the residual antibiotics with accuracy and convenience. Graphene-based electrochemical sensors are an effective tool to detect residual antibiotics owing to their advantages, such as, high sensitivity, simplicity, and time efficiency. In this work, we comprehensively summarize the recent advances in graphene-based electrochemical sensors used for detecting antibiotics, including modifiers for electrode fabrication, theoretical elaboration of electrochemical sensing mechanisms, and practical applications of portable electrochemical platforms for the on-site monitoring of antibiotics. It is anticipated that the current review will be a valuable reference for comprehensively comprehending graphene-based electrochemical sensors and further promoting their applications in the fields of healthcare, environmental protection, and food safety.