Voss B, Jankowsky H D
Comp Biochem Physiol B. 1986;83(1):13-22. doi: 10.1016/0305-0491(86)90325-1.
Temperature dependence of lipogenesis in trout liver cells was investigated in the presence of 5 mM lactate using either [14C]lactate or [3H]water. A ratio of 3H/14C-incorporation greater than one is found, irrespective of temperature. Acclimation of fish to 4, 10 or 16 degrees C affects neither the height of lipid synthesis nor its temperature sensitivity. The distribution of [14C]lactate between the main lipid classes and the capacities for cholesterol- and triacylglycerol-synthesis are correlated to the glycogen stores of the hepatocytes. A comparison of fatty acid synthesis and cholesterogenesis in livers of normal fed rat and of trout suggests a capability for lipogenesis in trout somewhat similar to that in mammals.
在5 mM乳酸存在的情况下，使用[14C]乳酸或[3H]水研究了虹鳟肝细胞脂肪生成的温度依赖性。无论温度如何，都发现3H/14C掺入比大于1。将鱼适应4、10或16摄氏度既不影响脂质合成的高度，也不影响其温度敏感性。[14C]乳酸在主要脂质类别之间的分布以及胆固醇和三酰甘油合成的能力与肝细胞的糖原储备相关。正常喂食的大鼠和虹鳟肝脏中脂肪酸合成和胆固醇生成的比较表明，虹鳟的脂肪生成能力与哺乳动物有些相似。
