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足月胎儿分离肝细胞中葡萄糖和酮体的生成——I. 母体禁食的影响

Glucose and ketone bodies production in hepatocytes isolated from fetuses at term--I. Effect of maternal fasting.

作者信息

Arahuetes R M, López J, Ramos M

出版信息

Comp Biochem Physiol B. 1986;83(1):227-9. doi: 10.1016/0305-0491(86)90357-3.

DOI:10.1016/0305-0491(86)90357-3
PMID:3943307
Abstract

The effect produced by maternal fasting on glucose and ketone bodies production has been studied in hepatocytes isolated from fetal rat. Maternal fasting produces a decrease in the weight of fetal liver. Maternal fasting produces a decrease in glucose production, both from endogenous substrates and adding lactate (10 mM) to the incubation medium. Maternal fasting produces an increase in ketone bodies production, both from endogenous substrates and adding acetate (5 mM) to the incubation medium.

摘要

母体禁食对从胎鼠分离的肝细胞中葡萄糖和酮体生成的影响已得到研究。母体禁食会导致胎肝重量减轻。母体禁食会使内源性底物生成葡萄糖以及向孵育培养基中添加乳酸(10 mM)时的葡萄糖生成量减少。母体禁食会使内源性底物生成酮体以及向孵育培养基中添加乙酸盐(5 mM)时的酮体生成量增加。

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