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一个经过验证的新生儿重症监护病房数据库:回顾50年的临床发展、质量改进与研究。

A validated NICU database: recounting 50 years of clinical growth, quality improvement and research.

作者信息

Babata Kikelomo, Rosenfeld Charles R, Jaleel Mambarambath, Burchfield Patti J, Oren Marina Santos, Albert Riya, Steven Brown L, Chalak Lina, Brion Luc P

机构信息

Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

University of Texas Southwestern Medical School, Dallas, TX, USA.

出版信息

Pediatr Res. 2024 Oct 21. doi: 10.1038/s41390-024-03624-3.

DOI:10.1038/s41390-024-03624-3
PMID:39433962
Abstract

The importance of a Neonatal Intensive Care Unit (NICU) database lies in its critical role in improving the quality of care for very preterm neonates and other high-risk newborns. These databases contain extensive information regarding maternal exposures, pregnancy complications, and neonatal care. They support quality improvement (QI) initiatives, facilitate clinical research, and track health outcomes in order to identify best practices and improve clinical guidelines. The Parkland Memorial Hospital NICU database was originally part of the Maternal and Neonatal Data Acquisition, Transmission and Evaluation project funded by the Robert Wood Johnson Foundation to assess perinatal-neonatal care in Dallas County Texas, 1977-1982. Clinical data points were defined, transcribed and validated in 1977; revalidation has occurred multiple times. Data are prospectively extracted from health records of high-risk neonates among >11,000 births annually. The database contains clinical information on >50,000 neonates, including all initially admitted to the NICU regardless of gestational age or birthweight and since 10/03/2011, all neonates admitted for observation and transferred to the term newborn nursery. The database has provided the basis for QI studies and research designed to assess and improve neonatal care. We discuss the history, evolution, administration, impact on neonatal outcomes, and future directions of our database. IMPACT: A single neonatal intensive care unit (NICU) database was designed for prospective data collection, validated and maintained for 46yrs. This database has supported quality improvement assessment, original clinical research, education and administrative requirements and impacted clinical neonatal care.

摘要

新生儿重症监护病房(NICU)数据库的重要性在于它在提高极早产儿和其他高危新生儿护理质量方面发挥的关键作用。这些数据库包含有关母亲暴露情况、妊娠并发症和新生儿护理的广泛信息。它们支持质量改进(QI)计划,促进临床研究,并跟踪健康结果,以确定最佳实践并改进临床指南。帕克兰纪念医院NICU数据库最初是由罗伯特·伍德·约翰逊基金会资助的孕产妇和新生儿数据采集、传输与评估项目的一部分,该项目旨在评估1977 - 1982年德克萨斯州达拉斯县的围产期 - 新生儿护理情况。临床数据点于1977年定义、转录并验证;多次进行了重新验证。数据前瞻性地从每年超过11000例分娩中的高危新生儿健康记录中提取。该数据库包含超过50000名新生儿的临床信息,包括所有最初入住NICU的新生儿,无论其孕周或出生体重如何,并且自2011年10月3日起,还包括所有因观察而入院并转入足月儿新生儿病房的新生儿。该数据库为旨在评估和改善新生儿护理的QI研究和调查提供了基础。我们讨论了我们数据库的历史、演变、管理、对新生儿结局的影响以及未来方向。影响:设计了一个单一的新生儿重症监护病房(NICU)数据库用于前瞻性数据收集,经过验证并维护了46年。该数据库支持质量改进评估、原创临床研究、教育和管理需求,并对临床新生儿护理产生了影响。

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本文引用的文献

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Pneumothorax in a term newborn.足月新生儿气胸。
J Perinatol. 2024 Apr;44(4):465-471. doi: 10.1038/s41372-024-01899-2. Epub 2024 Feb 26.
2
Maternal body mass index and necrotizing enterocolitis: A case-control study.母亲体质量指数与坏死性小肠结肠炎:病例对照研究。
PLoS One. 2024 Jan 24;19(1):e0296644. doi: 10.1371/journal.pone.0296644. eCollection 2024.
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Follow-up of a randomized trial optimizing neonatal nutrition in preterm very low birthweight infants: growth, serum adipokines, renal function and blood pressure.
一项优化早产儿极低出生体重儿营养的随机试验的随访:生长、血清脂肪因子、肾功能和血压。
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Growth after implementing a donor breast milk program in neonates <33 weeks gestational age or birthweight <1500 grams: Retrospective cohort study.实施捐赠母乳计划后 <33 周胎龄或出生体重 <1500 克的新生儿的生长情况:回顾性队列研究。
J Perinatol. 2023 May;43(5):608-615. doi: 10.1038/s41372-023-01627-2. Epub 2023 Feb 3.
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Double-blinded randomized controlled trial of optimizing nutrition in preterm very low birth weight infants: Bayley scores at 18-38 months of age.优化早产儿极低出生体重儿营养的双盲随机对照试验:18-38 个月时的贝利评分。
J Perinatol. 2023 Jan;43(1):81-85. doi: 10.1038/s41372-022-01572-6. Epub 2022 Dec 6.
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Decreasing Intubation for Ineffective Ventilation after Birth for Very Low Birth Weight Neonates.降低极低出生体重儿出生后无效通气时的插管率
Pediatr Qual Saf. 2022 Aug 1;7(4):e580. doi: 10.1097/pq9.0000000000000580. eCollection 2022 Jul-Aug.
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Persistent high blood pressure and renal dysfunction in preterm infants during childhood.早产儿儿童期持续性高血压和肾功能障碍
Pediatr Res. 2023 Jan;93(1):217-225. doi: 10.1038/s41390-022-02083-y. Epub 2022 Apr 28.
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Decreasing delivery room CPAP-associated pneumothorax at ≥35-week gestational age.降低≥35 孕周产房内 CPAP 相关气胸。
J Perinatol. 2022 Jun;42(6):761-768. doi: 10.1038/s41372-022-01334-4. Epub 2022 Feb 16.
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Association of antenatal steroids with surfactant administration in moderate preterm infants born to women with diabetes mellitus and/or hypertension.糖尿病和/或高血压孕妇所生的中度早产儿中,产前使用类固醇与表面活性剂治疗的关系。
J Perinatol. 2022 Aug;42(8):993-1000. doi: 10.1038/s41372-021-01273-6. Epub 2021 Nov 20.
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Decreasing early hypoglycemia frequency in at-risk newborns after implementing a new hypoglycemia screening algorithm.实施新的低血糖筛查算法后,降低高危新生儿的早期低血糖发生率。
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