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本文引用的文献

1
Donor Human Milk Use in Advanced Neonatal Care Units - United States, 2020.使用捐赠人类母乳的高级新生儿护理病房——美国，2020 年。
MMWR Morb Mortal Wkly Rep. 2022 Aug 19;71(33):1037-1041. doi: 10.15585/mmwr.mm7133a1.
2
Mother's Own Milk Compared With Formula Milk for Feeding Preterm or Low Birth Weight Infants: Systematic Review and Meta-analysis.母乳喂养与配方奶喂养早产儿或低出生体重儿的比较：系统评价和荟萃分析。
Pediatrics. 2022 Aug 1;150(Suppl 1). doi: 10.1542/peds.2022-057092D.
3
Exclusive Maternal Milk Compared With Exclusive Formula on Growth and Health Outcomes in Very-Low-Birthweight Preterm Infants: Phase II of the Pre-B Project and an Evidence Analysis Center Systematic Review.极低出生体重早产儿纯母乳喂养与纯配方奶喂养对生长和健康结局的影响：Pre - B项目的第二阶段及循证分析中心系统评价
Front Pediatr. 2022 Feb 25;9:793311. doi: 10.3389/fped.2021.793311. eCollection 2021.
4
The Association of Human Milk Feeding With Short-Term Health Outcomes Among Chinese Very/Extremely Low Birth Weight Infants.人乳喂养与中国极低/超低出生体重儿短期健康结局的关系。
J Hum Lact. 2022 Nov;38(4):670-677. doi: 10.1177/08903344221078237. Epub 2022 Mar 2.
5
Protein Enrichment of Donor Breast Milk and Impact on Growth in Very Low Birth Weight Infants.捐赠母乳的蛋白质富集及其对极低出生体重儿生长的影响。
Nutrients. 2021 Aug 20;13(8):2869. doi: 10.3390/nu13082869.
6
Nutrient composition of preterm mother's milk and factors that influence nutrient content.早产儿母乳的营养成分及其影响营养成分含量的因素。
Am J Clin Nutr. 2021 Nov 8;114(5):1719-1728. doi: 10.1093/ajcn/nqab226.
7
Human milk feeding and cognitive outcome in preterm infants: the role of infection and NEC reduction.人乳喂养与早产儿认知结局：感染和 NEC 减少的作用。
Pediatr Res. 2022 Apr;91(5):1207-1214. doi: 10.1038/s41390-021-01367-z. Epub 2021 Jun 24.
8
Human Milk Concentrations of Minerals, Essential and Toxic Trace Elements and Association with Selective Medical, Social, Demographic and Environmental Factors.人乳中矿物质、必需和有毒微量元素的浓度与某些医学、社会、人口和环境因素的关系。
Nutrients. 2021 May 31;13(6):1885. doi: 10.3390/nu13061885.
9
Effect of enteral zinc supplementation on growth and neurodevelopment of preterm infants: a systematic review and meta-analysis.肠内补锌对早产儿生长和神经发育的影响：系统评价和荟萃分析。
J Perinatol. 2022 Apr;42(4):430-439. doi: 10.1038/s41372-021-01094-7. Epub 2021 May 18.
10
Zinc levels in neonatal life influence long-term neurodevelopment.新生儿期的锌水平会影响长期神经发育。
J Perinatol. 2021 May;41(5):1196-1197. doi: 10.1038/s41372-021-01012-x. Epub 2021 Mar 23.

实施捐赠母乳计划后 <33 周胎龄或出生体重 <1500 克的新生儿的生长情况：回顾性队列研究。

Growth after implementing a donor breast milk program in neonates <33 weeks gestational age or birthweight <1500 grams: Retrospective cohort study.

机构信息

Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Division of Neonatology, Joe DiMaggio Children's Hospital, Hollywood, FL, USA.

出版信息

J Perinatol. 2023 May;43(5):608-615. doi: 10.1038/s41372-023-01627-2. Epub 2023 Feb 3.

DOI:10.1038/s41372-023-01627-2
PMID:36737571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9897884/
Abstract

BACKGROUND

Donor breast milk (DBM) feeding has been associated with less growth than formula in preterm infants. Zinc content in DBM is insufficient to support growth in preterm infants.

OBJECTIVE

To compare growth from birth to discharge, macro- and micronutrient intake and the frequency of poor growth before (Epoch-1) and after (Epoch-2) implementing a DBM program.

METHODS

Retrospective cohort study of 1069 infants born at < 33 weeks' gestational age or birthweight < 1500 g and fed using our adjustable feeding protocol with accurate serial length measurements. Growth was assessed by changes in Z-scores of weight, length and fronto-occipital circumference from birth to discharge.

RESULTS

Growth did not decrease significantly in Epoch-2. However, energy and protein intake increased by 5% and frequency of zinc and vitamin D supplementation increased by >30%.

CONCLUSIONS

DBM implementation did not significantly decrease growth from birth to discharge using our adjustable feeding protocol.

摘要

背景

与配方奶相比，捐赠母乳（DBM）喂养会导致早产儿生长较慢。DBM 中的锌含量不足以支持早产儿的生长。

目的

比较从出生到出院的生长情况、宏量和微量营养素的摄入量，以及在实施 DBM 计划之前（Epoch-1）和之后（Epoch-2）生长不良的频率。

方法

对 1069 名胎龄<33 周或出生体重<1500g 的早产儿进行回顾性队列研究，使用我们的可调节喂养方案进行喂养，并进行准确的连续长度测量。通过出生至出院时体重、长度和头围 Z 分数的变化来评估生长情况。

结果

在 Epoch-2 中，生长并没有显著下降。然而，能量和蛋白质的摄入量增加了 5%，锌和维生素 D 补充的频率增加了>30%。

结论

使用我们的可调节喂养方案，实施 DBM 并不会显著降低从出生到出院的生长速度。