Odrobina Dominik, Gołębiewska Joanna, Maroszyńska Iwona
*Ophthalmology Clinic of St. John Boni Fratres Lodziensis, Łódź, Poland; †Faculty of Health Sciences, Jan Kochanowski Memorial University of Kielce, Kielce, Poland; ‡Department of Ophthalmology, Children's Memorial Health Institute, Warsaw, Poland; and §Department of Intensive Care and Congenital Malformations of Neonates and Infants, Polish Mother's Memorial Hospital-Research Institute, Łódź, Poland.
Retina. 2017 Nov;37(11):2124-2129. doi: 10.1097/IAE.0000000000001437.
To access the potential effect of vitrectomy and silicone oil tamponade on the choroid.
Eighteen patients (18 eyes) who had undergone pars plana vitrectomy with 1,000-cSt silicone oil tamponade for proliferative vitreoretinopathy retinal detachment were included in this retrospective study. All patients underwent ophthalmologic examinations before treatment and 1 week and 1, 3, and 6 months after vitrectomy with silicone oil tamponade. Choroidal thickness was measured using enhanced depth imaging optical coherence tomography (Spectralis; Heidelberg Engineering) in a horizontal and vertical section beneath the fovea.
Choroidal thickness statistically significantly decreased till 3 months after pars plana vitrectomy with silicone oil tamponade: under the center of the fovea (P = 0.014) and in the temporal (P = 0.029), superior (P = 0.046), and inferior areas, determined at 1,500 μm from the center of the fovea (P = 0.030). After 6 months, the desired effect in the form of a decrease in the choroidal thickness was even more prominent, both under the center of the fovea (P < 0.001) and in the nasal (P < 0.001), temporal (P < 0.001), superior (P < 0.001), and inferior areas at 1,500 μm from the center of the fovea (P < 0.001).
Choroidal thickness is reduced in eyes receiving silicone oil intraocular tamponade. Silicone oil tamponade may have an impact on the structure and proper functioning of the choroid. The measurements of the choroidal thickness by optical coherence tomography might be a very good tool to detect early changes in choroidal thickness and impact the decision when to remove silicone oil.
探讨玻璃体切除术联合硅油填充对脉络膜的潜在影响。
本回顾性研究纳入18例（18眼）因增生性玻璃体视网膜病变视网膜脱离行平坦部玻璃体切除术联合1000厘沲硅油填充的患者。所有患者在治疗前、玻璃体切除联合硅油填充术后1周、1个月、3个月和6个月均接受眼科检查。使用增强深度成像光学相干断层扫描（Spectralis；海德堡工程公司）在黄斑中心凹下方的水平和垂直截面测量脉络膜厚度。
在平坦部玻璃体切除术联合硅油填充术后3个月内，脉络膜厚度在统计学上显著降低：在黄斑中心凹下方（P = 0.014）以及在距黄斑中心凹1500μm处的颞侧（P = 0.029）、上方（P = 0.046）和下方区域（P = 0.030）。6个月后，脉络膜厚度降低的预期效果更加显著，在黄斑中心凹下方（P < 0.001）以及在距黄斑中心凹1500μm处的鼻侧（P < 0.001）、颞侧（P < 0.001）、上方（P < 0.001）和下方区域（P < 0.001）均如此。
接受硅油眼内填充的眼睛脉络膜厚度会降低。硅油填充可能会对脉络膜的结构和正常功能产生影响。通过光学相干断层扫描测量脉络膜厚度可能是检测脉络膜厚度早期变化以及影响硅油取出时机决策的一个很好的工具。
