Korkmaz Buse, Yaşa Mustafa Ertuğrul, Sonkaya Rıza
Gulhane Faculty of Physiotherapy and Rehabilitation, University of Health Sciences, Ankara, Turkey.
Gulhane School of Medicine, Neurology Department, University of Health Sciences, Ankara, Turkey.
Acta Neurol Belg. 2025 Feb;125(1):119-126. doi: 10.1007/s13760-024-02656-0. Epub 2024 Oct 22.
Upper extremity dysfunction is frequently seen in Parkinson's disease (PD). Existing research has shown that bradykinesia, which is main symptom of PD, is primarily responsible but the combined effects of spinal posture and axial rigidity on upper extremity functions were not investigated yet. The aim of this study was to investigate upper extremity functions in patients with PD and to evaluate relationship of these with spinal posture and axial rigidity.
This prospective controlled study included 40 patients with PD and 40 healthy controls. Upper extremity function was measured with the 9-Hole Peg Test. Spinal posture and axial rigidity were measured with a Spinal Mouse.
Compared with the control group, a decrease in upper extremity functions (p < 0.001), decreased lumbar lordosis (p = 0.003), and posterior sacral tilt (p = 0.021) were determined in patients' group. Thoracic and lumbar mobility in the sagittal (all p < 0.001) and frontal planes (p = 0.004, p < 0.001) was found to be reduced in the patient group. A correlation was determined between upper extremity functions and lumbar mobility in the sagittal (p = 0.022, r= -0.362) and frontal planes (p = 0.045, r= -0.319) and lumbar lordosis (p = 0.048, r = 0.302).
The results of this study demonstrated that altered spinal posture and increased axial rigidity were related with decreased upper extremity functions in patients with PD. There is a need for further studies to investigate effect of trunk-based therapies on upper extremity function in patients with PD.
上肢功能障碍在帕金森病（PD）中很常见。现有研究表明，作为PD主要症状的运动迟缓是主要原因，但尚未研究脊柱姿势和轴向僵硬对上肢功能的综合影响。本研究的目的是调查PD患者的上肢功能，并评估这些功能与脊柱姿势和轴向僵硬的关系。
这项前瞻性对照研究包括40例PD患者和40名健康对照者。用9孔插钉试验测量上肢功能。用脊柱鼠标测量脊柱姿势和轴向僵硬。
与对照组相比，患者组上肢功能下降（p < 0.001），腰椎前凸减小（p = 0.003），骶骨后倾（p = 0.021）。发现患者组在矢状面（所有p < 0.001）和额状面（p = 0.004，p < 0.001）的胸腰椎活动度降低。确定上肢功能与矢状面（p = 0.022，r = -0.362）和额状面（p = 0.045，r = -0.319）的腰椎活动度以及腰椎前凸（p = 0.048，r = 0.302）之间存在相关性。
本研究结果表明，脊柱姿势改变和轴向僵硬增加与PD患者上肢功能下降有关。需要进一步研究以调查基于躯干的治疗对PD患者上肢功能的影响。
