Department of Pharmacy, Massachusetts General Hospital, 55 Fruit Street, Boston, MA.
Department of Pharmacy, Denver Health and Hospital Authority, 777 Bannock Street, Denver, CO.
NEJM Evid. 2024 Nov;3(11):EVIDra2300347. doi: 10.1056/EVIDra2300347. Epub 2024 Oct 22.
AbstractSedation practices are key to improving intensive care unit (ICU) outcomes. Adequate treatment of pain, minimization of sedation, delirium prevention, and improved patient interaction to ensure early rehabilitation and faster ventilator liberation are evidenced-based components of ICU care. Here we review components of appropriate ICU sedation including the use of multicomponent care bundles such as the ABCDEF bundle with a focus on changes in ICU practice that followed the Covid-19 pandemic.
镇静实践是改善重症监护病房（ICU）治疗结果的关键。充分治疗疼痛、最小化镇静、预防谵妄，以及改善患者互动以确保早期康复和更快地脱离呼吸机，这些都是 ICU 治疗的循证组成部分。在这里，我们回顾了适当的 ICU 镇静的组成部分，包括使用多组分护理包，如 ABCDEF 包，并重点介绍了新冠肺炎大流行后 ICU 实践的变化。
