Jacobs G, Hutson C, Dougherty J, Kirmayer A
J Am Vet Med Assoc. 1986 Jan 1;188(1):52-6.
Hyperthyroidism was diagnosed in 4 cats with congestive heart failure. Dyspnea and anorexia were observed in 3 of the 4 cats. In each cat, a holosystolic left and/or right apical heart murmur was auscultated. In 3 cats, a prominent extra heart sound (gallop rhythm) was auscultated. All cats had a palpably large thyroid lobe(s) and weight loss. The laboratory and ECG changes were similar to those reported for feline hyperthyroidism. Moderate-to-severe pleural effusion and cardiomegaly were detected via radiography in all cats. Some cats had radiographic signs of pulmonary venous engorgement and pulmonary edema. Echocardiography revealed cardiac dilatation and low left ventricular shortening fraction (wall motion) in all cats. Three cats responded initially to cardiac drugs and propylthiouracil or thyroidectomy. One of these died later, presumably from an adverse reaction to propylthiouracil, and the others died from recurrent congestive heart failure (1) or postoperative cardiac arrest (1). One cat did not respond to treatment, and died 2 days after diagnosis.
4只患有充血性心力衰竭的猫被诊断为甲状腺功能亢进。4只猫中有3只出现呼吸困难和厌食。每只猫听诊时均闻及全收缩期左和/或右心尖部心脏杂音。3只猫听诊时闻及明显的心外额外心音（奔马律）。所有猫均可触及甲状腺叶肿大且体重减轻。实验室检查和心电图变化与报道的猫甲状腺功能亢进相似。所有猫经X线检查均发现中至重度胸腔积液和心脏增大。部分猫有肺静脉充血和肺水肿的X线征象。超声心动图显示所有猫均有心脏扩张和左心室缩短分数降低（室壁运动）。3只猫最初对心脏药物及丙硫氧嘧啶或甲状腺切除术有反应。其中1只后来死亡，推测死于丙硫氧嘧啶不良反应，其他死于复发性充血性心力衰竭（1只）或术后心脏骤停（1只）。1只猫对治疗无反应，诊断后2天死亡。
