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用于分娩时硬膜外镇痛不足的标准化追加硬膜外药物算法的实施:一项单中心回顾性研究

Implementation of a standardized epidural top-up algorithm for inadequate labor epidural analgesia: a single-center retrospective study.

作者信息

Zeitz Jack, Waddle Anne, Long Sloan, Grote Dylan, Sorrels Cole, Hofkamp Michael P

机构信息

Texas A&M University School of Medicine, College Station, Texas, USA.

Department of Anesthesiology, Baylor Scott & White Medical Center - Temple, Temple, Texas, USA.

出版信息

Proc (Bayl Univ Med Cent). 2024 Sep 12;37(6):908-913. doi: 10.1080/08998280.2024.2401739. eCollection 2024.

Abstract

BACKGROUND

We hypothesized that implementation of a labor epidural management algorithm would increase the labor epidural catheter replacement rate at our hospital.

METHODS

Our institutional review board approved this study and waived the requirement for informed consent. Patients who had labor epidural analgesia and delivered vaginally or had replacement of an epidural catheter prior to vaginal delivery from August 1, 2022 to December 31, 2022 and from August 1, 2023 to December 31, 2023 were included in the study. Study investigators entered data from the electronic medical record into REDCap.

RESULTS

A total of 530 and 740 patients received labor epidural analgesia and met inclusion criteria before and after implementation of the algorithm, respectively. Patients who received labor epidural analgesia after implementation of the protocol had an absolute increase of 1.0% in the catheter replacement rate, which was not statistically significant ( = 0.34). A multivariate logistic regression found that the number or rescue analgesia boluses (odds ratio 2.68; 95% confidence interval 2.092, 3.434;  < 0.001) and operator level of training (odds ratio 0.41; 95% confidence interval 0.226, 0.743;  = 0.003) were associated with catheter replacement.

CONCLUSION

After implementation of a labor epidural catheter management algorithm, patients had an increase in labor epidural catheter replacement that was not statistically significant.

摘要

背景

我们假设实施一项产时硬膜外管理算法会提高我院产时硬膜外导管更换率。

方法

我们的机构审查委员会批准了本研究并豁免了知情同意的要求。纳入2022年8月1日至2022年12月31日以及2023年8月1日至2023年12月31日期间接受产时硬膜外镇痛并经阴道分娩或在阴道分娩前更换硬膜外导管的患者。研究调查人员将电子病历中的数据录入REDCap。

结果

分别有530例和740例患者在实施该算法前后接受了产时硬膜外镇痛并符合纳入标准。实施该方案后接受产时硬膜外镇痛的患者导管更换率绝对增加了1.0%,但差异无统计学意义(P = 0.34)。多因素逻辑回归分析发现,补救性镇痛推注次数(比值比2.68;95%置信区间2.092,3.434;P < 0.001)和操作人员培训水平(比值比0.41;95%置信区间0.226,0.743;P = 0.003)与导管更换有关。

结论

实施产时硬膜外导管管理算法后,患者产时硬膜外导管更换率有所增加,但差异无统计学意义。

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