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突尼斯单侧唇腭裂儿童的牙齿成熟度是否与正常个体不同?一项初步研究。

Do Tunisian children with unilateral cleft lip and palate differ from normal individuals in dental maturity? A pilot study.

机构信息

Department of Pediatric Dentistry, La Rabta University Hospital, Tunis, Tunisia.

Research Laboratory: Dento-facial biological and clinical approach LR12ES10, University of Monastir, Tunisia.

出版信息

Tunis Med. 2024 Oct 5;102(10):641-646. doi: 10.62438/tunismed.v102i10.4907.

DOI:10.62438/tunismed.v102i10.4907
PMID:39441161
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11574380/
Abstract

INTRODUCTION

Cleft lip and palate (CLP) is the most common congenital malformation of the head and neck. Children with CLP often exhibit dental anomalies.

AIM

To evaluate the dental age (DA) of unilateral CLP in Tunisian children.

METHODS

This was a cross-sectional study carried out in the department of pediatric dentistry at the University Hospital La Rabta, Tunis. Patients aged between 5 and 14 years, with no other congenital anomalies or syndromes in the craniofacial region other than CLP, were included. The patients' chronological ages were first calculated in years and months. DA was assessed in panoramic radiographs using Demirjian's method. The score of each stage is allocated, and the sum of the scores provides an evaluation of the subject's dental maturity.

RESULTS

Fifty-three patients were included in the present study. No difference was observed between the two groups regarding the dental age. A strong and positive correlation between the DA and the chronological age in the two groups was observed (r=0.826). Estimated regression showed that chronological age alone explained 57,4% (r2=0.574) of the dental age variation in the study group and 64.5% (r2=0.645) in the control group.

CONCLUSION

For dental management, CLP children should have the same approach in orthodontics and pediatric dentistry as individuals without clefts, with a focus on the individualization of diagnosis and treatment planning.

摘要

引言

唇腭裂(CLP)是头颈部最常见的先天性畸形。CLP 患儿常伴有牙齿畸形。

目的

评估突尼斯单侧 CLP 儿童的牙龄(DA)。

方法

这是一项在突尼斯拉巴特大学医院儿科牙科系进行的横断面研究。纳入年龄在 5 至 14 岁之间,除 CLP 外,头面部无其他先天性异常或综合征的患者。患者的实际年龄首先以年和月计算。DA 通过 Demirjian 法在全景片上进行评估。为每个阶段分配评分,总评分提供对受试者牙齿成熟度的评估。

结果

本研究共纳入 53 例患者。两组之间的牙龄无差异。两组中 DA 与实际年龄之间存在强烈的正相关(r=0.826)。估计回归显示,在研究组中,实际年龄单独解释了 57.4%(r2=0.574)的牙龄变化,在对照组中解释了 64.5%(r2=0.645)。

结论

对于牙科管理,CLP 患儿在正畸和儿科牙科方面应与无裂隙的个体采用相同的方法,重点是个体化诊断和治疗计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0d/11574380/b777485298d4/capture7.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0d/11574380/d32ef5a9c824/capture1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0d/11574380/569ee548f5d7/capture2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0d/11574380/28286cb2df0b/capture3.jpg
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本文引用的文献

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Orofacial Clefts: Genetics of Cleft Lip and Palate.口腔颌面部裂隙:唇腭裂的遗传学。
Genes (Basel). 2023 Aug 9;14(8):1603. doi: 10.3390/genes14081603.
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Frequency of Additional Congenital Dental Anomalies in Children with Cleft Lip, Alveolar and Palate.唇腭裂儿童额外先天性牙齿异常的发生率
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Prevalence of Dental Anomalies in the Patient with Cleft Lip and Palate Visiting a Tertiary Care Hospital.唇腭裂患者口腔颌面部先天畸形的调查分析。
JNMA J Nepal Med Assoc. 2020 Aug 31;58(228):591-596. doi: 10.31729/jnma.5149.
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Clin Oral Investig. 2021 May;25(5):2619-2631. doi: 10.1007/s00784-020-03573-1. Epub 2020 Sep 10.
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Evaluation of Dental Age in Individuals of Different Ages with Unilateral Cleft Lip and Palate.不同年龄单侧唇腭裂患者牙齿发育年龄的评估
Turk J Orthod. 2020 May 18;33(2):103-109. doi: 10.5152/TurkJOrthod.2020.19094. eCollection 2020 Jun.
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Cleft Lip and Palate.唇腭裂
Clin Perinatol. 2018 Dec;45(4):661-678. doi: 10.1016/j.clp.2018.07.006. Epub 2018 Sep 18.
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An optimized imaging protocol for orofacial cleft patients.一种针对口腔颌面裂患者的优化成像方案。
Clin Exp Dent Res. 2018 Jul 25;4(5):152-157. doi: 10.1002/cre2.123. eCollection 2018 Oct.
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The Demirjian versus the Willems method for dental age estimation in different populations: A meta-analysis of published studies.不同人群中用于牙齿年龄估计的德米尔坚法与威廉姆斯法:已发表研究的荟萃分析
PLoS One. 2017 Nov 8;12(11):e0186682. doi: 10.1371/journal.pone.0186682. eCollection 2017.
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Cleft Lip and Palate: An Experience of a Developing Center in Egypt.唇腭裂:埃及一家发展中的中心的经验
J Craniofac Surg. 2017 Nov;28(8):e731-e734. doi: 10.1097/SCS.0000000000003870.
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Longitudinal dental maturation of children with complete unilateral cleft lip and palate: A case-control cohort study.单侧完全性唇腭裂儿童的牙齿纵向萌出:一项病例对照队列研究。
Orthod Craniofac Res. 2017 Nov;20(4):189-195. doi: 10.1111/ocr.12196. Epub 2017 Jul 24.