McCollough N C, Enis J E, Lovitt J, Lian E C, Niemann K N, Loughlin E C
J Bone Joint Surg Am. 1979 Jan;61(1):69-75.
Eighteen major operations on the knee joint were performed in sixteen patients with hemophilia, eight operations being synovectomy and ten being total knee replacement. Synovectomy was performed for recurrent bleeding associated with synovitis. The average age at operation for patients who underwent synovectomy was 16.4 years, and the average follow-up was thirty-one months. No patient had a recurrent hemorrhage following synovectomy. The patients who had total knee arthroplasty for disabling pain had an average age at surgery of 35.7 years and an average follow-up of twenty-three months. The pain was markedly reduced in all eight patients and all achieved full unprotected weight-bearing. Loss of some motion was observed in twelve patients, but the functional gain outweighed the loss of knee mobility. Seven major complications occurred in the sixteen patients, but none of them affected the outcome.
对16名血友病患者的膝关节进行了18次大手术，其中8例为滑膜切除术，10例为全膝关节置换术。滑膜切除术用于治疗与滑膜炎相关的反复出血。接受滑膜切除术患者的平均手术年龄为16.4岁，平均随访时间为31个月。滑膜切除术后无患者出现复发性出血。因疼痛致残而接受全膝关节置换术的患者平均手术年龄为35.7岁，平均随访时间为23个月。所有8例患者的疼痛均明显减轻，且均实现了完全无保护负重。12例患者出现了一定程度的活动度丧失，但功能改善超过了膝关节活动度的丧失。16例患者发生了7例严重并发症，但均未影响手术结果。
