Takahashi Yosuke, Morisaki Akimasa, Sakon Yoshito, Nishiya Kenta, Inno Goki, Kawase Takumi, Nishimoto Yukihiro, Nagao Munehide, Noda Kazuki, Aoyama Takanobu, Shibata Toshihiko
Department of Cardiovascular Surgery, Osaka Metropolitan University Postgraduate School of Medicine, Asahimachi, Abeno, Osaka, Japan.
Department of Cardiovascular Surgery, Osaka City General Hospital, Miyakojimaku, Osaka, Japan.
J Thorac Dis. 2024 Sep 30;16(9):5494-5506. doi: 10.21037/jtd-24-593. Epub 2024 Sep 10.
Left atrial (LA) plication is a procedure used to correct an LA that expands posteriorly due to remodeling. This study aimed to determine the efficacy of additional LA plication in reducing postoperative cardiovascular events (CVEs) after mitral valve (MV) repair in atrial functional mitral regurgitation (MR) patients.
Between October 2008 and August 2023, MV repair with or without LA plication in 74 patients was studied. This study examined the efficacy of concomitant LA plication during MV repair.
All patients underwent mitral annuloplasty. Of these, 26 underwent additional LA plication. In the mid-term periods, protruding posterior LA length in patients with LA plication was shorter than those without LA plication (2.8±0.49 . 3.3±0.72 cm, P=0.01). The percentage change in aortomitral angle from preoperative to mid-term periods in patients with LA plication was bigger than those without LA plication (1.04°±0.102° . 0.98°±0.084°, P=0.01). Posterior leaflet coaptation angle in patients with LA plication was smaller than those without LA plication (42°±15° . 76°±30°, P<0.001). A postoperative posterior leaflet coaptation angle of 101° had the maximum sum of sensitivity and specificity in predicting postoperative CVEs (96.9% and 76.9%, respectively). Patients with a postoperative posterior leaflet coaptation angle of 101° or higher had a poorer prognosis than those with an angle less than 101°, with an event-free rate of 18% . 80% at 7 years after surgery (P<0.0001).
Additional LA plication might be useful in reducing postoperative CVEs in atrial functional MR patients.
左心房(LA)折叠术是一种用于纠正因重塑而向后扩张的左心房的手术。本研究旨在确定在功能性二尖瓣反流(MR)患者二尖瓣(MV)修复术后,额外的左心房折叠术在减少术后心血管事件(CVE)方面的疗效。
研究了2008年10月至2023年8月期间74例行或不行左心房折叠术的二尖瓣修复患者。本研究探讨了二尖瓣修复术中同期行左心房折叠术的疗效。
所有患者均接受二尖瓣环成形术。其中,26例患者接受了额外的左心房折叠术。在中期,行左心房折叠术患者的左心房后凸长度短于未行左心房折叠术的患者(2.8±0.49对3.3±0.72cm,P = 0.01)。行左心房折叠术患者从术前到中期主动脉二尖瓣角的百分比变化大于未行左心房折叠术的患者(1.04°±0.102°对0.98°±0.084°,P = 0.01)。行左心房折叠术患者的后叶对合角小于未行左心房折叠术的患者(42°±15°对76°±30°,P<0.001)。术后后叶对合角为101°时,预测术后心血管事件的敏感性和特异性之和最高(分别为96.9%和76.9%)。术后后叶对合角为101°或更高的患者预后比角度小于101°的患者差,术后7年无事件发生率为18%对80%(P<0.0001)。
额外的左心房折叠术可能有助于减少功能性二尖瓣反流患者术后的心血管事件。