Otis Joanna L, Parker Nicholas M, Busch Rebecca A
Department of Clinical Nutrition, University of Wisconsin Hospital and Clinics, Madison, Wisconsin, USA.
Department of Pharmacy, University of Wisconsin Hospital and Clinics, Madison, Wisconsin, USA.
Nutr Clin Pract. 2025 Feb;40(1):35-53. doi: 10.1002/ncp.11231. Epub 2024 Oct 24.
Providing optimal nutrition support in the intensive care unit (ICU) is a challenging and dynamic process. Energy, protein, fluid, electrolyte, and micronutrient requirements all can be altered in patients with acute, chronic, and acute-on-chronic kidney disease. Given that renal dysfunction occurs in up to one-half of ICU patients, it is imperative that nutrition support providers understand how renal dysfunction, its metabolic consequences, and its treatments, including renal replacement therapy (RRT), affect patients' nutrition needs. Data on nutrient requirements in critically ill patients with renal dysfunction are sparse. This article provides an overview of renal dysfunction in the ICU and identifies and addresses the unique nutrition challenges present among these patients, including those receiving RRT, as supported by the available literature and guidelines.
在重症监护病房(ICU)提供最佳营养支持是一个具有挑战性且动态变化的过程。急性、慢性及慢性急性肾损伤患者的能量、蛋白质、液体、电解质和微量营养素需求均可能发生改变。鉴于多达一半的ICU患者会出现肾功能障碍,营养支持提供者必须了解肾功能障碍、其代谢后果及其治疗方法(包括肾脏替代治疗[RRT])如何影响患者的营养需求。关于肾功能不全重症患者营养需求的数据稀少。本文概述了ICU中的肾功能障碍,并根据现有文献和指南,识别并阐述了这些患者(包括接受RRT的患者)所面临的独特营养挑战。