阿托品或格隆溴铵与5毫克新斯的明：一项比较剂量反应研究。
Atropine or glycopyrrolate with neostigmine 5 mg: a comparative dose-response study.
作者信息
Salem M G, Ahearn R S
出版信息
J R Soc Med. 1986 Jan;79(1):19-21. doi: 10.1177/014107688607900107.
Abstract
One hundred and fifteen patients, separated into 4 groups, received neostigmine 5 mg with either atropine 1.2 mg or 1.8 mg, or glycopyrrolate 0.6 mg or 0.9 mg. Those receiving 0.9 mg glycopyrrolate had insignificant changes in heart rate in the immediate postreversal period. It is recommended that when glycopyrrolate is used with 5 mg neostigmine, the optimum dose is 0.9 mg.
摘要
115名患者被分成4组，分别接受新斯的明5毫克与阿托品1.2毫克或1.8毫克，或格隆溴铵0.6毫克或0.9毫克的治疗。接受0.9毫克格隆溴铵治疗的患者在逆转后即刻心率变化不明显。建议当格隆溴铵与5毫克新斯的明联用时，最佳剂量为0.9毫克。
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