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调查职业暴露人群异常肺通气功能的影响因素,并建立风险预测模型。

Investigation of factors influencing abnormal pulmonary ventilation function in occupational exposed populations and the establishment of a risk prediction model.

机构信息

Department of Pulmonary and Critical Care Medicine, Jiangmen Institute of Respiratory Disease, Jiangmen Central Hospital, Jiangmen, People's Republic of China.

Dongguan Key Laboratory of Environmental Medicine, Department of Environmental and Occupational Health, School of Public Health, Guangdong Medical University, Dongguan, 523808, People's Republic of China.

出版信息

Sci Rep. 2024 Oct 24;14(1):25215. doi: 10.1038/s41598-024-76412-y.

Abstract

The purpose of this study is to investigate the influencing factors of abnormal pulmonary ventilation function in occupational exposed populations and to establish a risk prediction model. The findings will provide a basis for formulating corresponding strategies for the prevention and treatment of occupational diseases. The study focused on workers who underwent occupational health examinations in the year 2020. Statistical analysis was conducted using methods such as t-tests, chi-square tests, and multiple logistic regression analysis. Additionally, machine learning methods were employed to establish multiple models to address classification problems. Among the 7472 workers who participated in the occupational health examination, 1681 cases of abnormal pulmonary ventilation function were detected, resulting in a detection rate of 22.6%. Based on the analysis of occupational hazard data, a risk prediction model was established. Age, work tenure, type of the employing enterprise, and type of dust exposure are all identified as driving factors for abnormal pulmonary function. These factors were used as predictive variables for establishing the risk prediction model. Among the various models evaluated, the logistic regression model was found to be the optimal model for predicting abnormal pulmonary ventilation function.

摘要

本研究旨在探讨职业暴露人群肺通气功能异常的影响因素,并建立风险预测模型。研究结果将为制定相应的职业病防治策略提供依据。本研究对象为 2020 年接受职业健康检查的劳动者。采用 t 检验、卡方检验和多因素 Logistic 回归分析等方法进行统计学分析。同时,采用机器学习方法建立多个模型来解决分类问题。在 7472 名参加职业健康检查的劳动者中,检出肺通气功能异常 1681 例,检出率为 22.6%。基于职业危害因素分析,建立了风险预测模型。年龄、工龄、企业类型和粉尘接触类型均为肺功能异常的驱动因素。这些因素被用作建立风险预测模型的预测变量。在评价的各种模型中,Logistic 回归模型被发现是预测肺通气功能异常的最优模型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5fe/11502800/5879b71a351a/41598_2024_76412_Fig1_HTML.jpg

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