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一项功能性运动方案可改善纤维肌痛患者的疼痛和健康相关生活质量:一项随机对照试验。

A functional exercise program improves pain and health related quality of life in patients with fibromyalgia: a randomized controlled trial.

机构信息

Rheumatology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Botucatu, 740, São Paulo, SP, CEP: 04023-900, Brazil.

出版信息

Adv Rheumatol. 2024 Oct 24;64(1):81. doi: 10.1186/s42358-024-00422-7.

DOI:10.1186/s42358-024-00422-7
PMID:39449056
Abstract

BACKGROUND/OBJECTIVE: Fibromyalgia is a non-inflammatory syndrome characterized by generalized muscle pain, with other symptoms. Numerous forms of physical training for this population have been studied through high-quality randomized clinical trials involving strength, flexibility, aerobic conditioning and multicomponent exercise interventions. This research evaluated the effectiveness of a functional exercise program at reducing pain, improving functional capacity, increasing muscle strength as well as improving flexibility, balance and quality of life in individuals with fibromyalgia.

METHODS

Eighty-two women with fibromyalgia were randomized into two groups. The functional exercise group performed functional exercises in 45-minute sessions twice per week for 14 weeks. The stretching exercise group performed flexibility exercises with the same duration and frequency. Outcome measures were: visual analog scale for widespread pain; Fibromyalgia Impact Questionnaire for health-related quality of life; Timed Up and Go test for functional performance; one-repetition maximum for muscle strength, Sit and Reach test on Wells bench for flexibility; Berg Balance Scale for balance; SF-36 for general quality of life.

RESULTS

After the intervention, the functional exercise group had a statistically significant reduction in pain (interaction p = 0.002), and improvement in health-related quality of life measured by the Fibromyalgia Impact Questionnaire (interaction p < 0.001) and in general health state domain of SF-36 (interaction p = 0.043) compared to the stretching exercise group. No significant differences between groups were found regarding improvements in functional capacity, muscle strength, flexibility or balance.

CONCLUSION

Functional exercise training was effective at reducing pain and improving quality of life in patients with fibromyalgia compared to stretching exercises.

TRIAL REGISTRATION

ClinicalTrials.gov Identifier: NCT03682588 First prospectively registered in March 2018.

摘要

背景/目的:纤维肌痛是一种非炎症性综合征,其特征为全身性肌肉疼痛,并伴有其他症状。大量针对该人群的身体训练形式已经通过高质量的随机临床试验进行了研究,这些试验涉及力量、柔韧性、有氧健身和多成分运动干预。本研究评估了一项功能性运动方案在减轻疼痛、改善功能能力、增加肌肉力量以及提高柔韧性、平衡和生活质量方面对纤维肌痛患者的有效性。

方法

82 名纤维肌痛女性患者被随机分为两组。功能性运动组每周进行两次、每次 45 分钟的功能性运动,共进行 14 周。伸展运动组进行相同时长和频率的柔韧性运动。评估结果包括:广泛疼痛的视觉模拟量表;纤维肌痛影响问卷评估健康相关生活质量;计时起立-行走测试评估功能表现;一次重复最大量评估肌肉力量;Wells bench 坐立伸展测试评估柔韧性;伯格平衡量表评估平衡;SF-36 评估一般生活质量。

结果

干预后,与伸展运动组相比,功能性运动组的疼痛明显减轻(交互作用 p=0.002),纤维肌痛影响问卷评估的健康相关生活质量得到改善(交互作用 p<0.001),SF-36 评估的一般健康状况领域也得到改善(交互作用 p=0.043)。两组在功能能力、肌肉力量、柔韧性或平衡方面的改善均无显著差异。

结论

与伸展运动相比,功能性运动训练可有效减轻纤维肌痛患者的疼痛,改善生活质量。

试验注册

ClinicalTrials.gov 标识符:NCT03682588 于 2018 年 3 月首次前瞻性注册。

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Sci Rep. 2022 Jun 20;12(1):10391. doi: 10.1038/s41598-022-14213-x.
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Effects of different protocols of physical exercise on fibromyalgia syndrome treatment: systematic review and meta-analysis of randomized controlled trials.不同运动方案治疗纤维肌痛综合征的效果:随机对照试验的系统评价和荟萃分析。
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Multidisciplinary rehabilitation treatments for patients with fibromyalgia: a systematic review.
纤维肌痛症患者的多学科康复治疗:系统评价。
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Comparison of weight bearing functional exercise and non-weight bearing quadriceps strengthening exercise on pain and function for people with knee osteoarthritis and obesity: protocol for the TARGET randomised controlled trial.比较负重功能锻炼和非负重股四头肌强化锻炼对膝骨关节炎合并肥胖患者疼痛和功能的影响:TARGET 随机对照试验方案。
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