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探讨体重指数与肺功能测试参数之间的相关性:一项横断面分析研究。

Exploring the correlation between body mass index and lung function test parameters: a cross-sectional analytical study.

机构信息

Department of Public Health and Community Medicine, Damietta Faculty of Medicine, Al- Azhar University, Cairo, Egypt.

Occupational Medicine physician, Sadara Chemical Company, Eastern province, Jubail, Saudi Arabia.

出版信息

BMC Res Notes. 2024 Oct 24;17(1):320. doi: 10.1186/s13104-024-06967-6.

Abstract

PURPOSE

The correlation between body weight and health is a significant public health concern. While the adverse effects of obesity on pulmonary function are well-known, the impact of being underweight remains debated due to limited research. This study aimed to investigate the correlation between Body Mass Index (BMI) categories and lung function parameters.

RESULTS

A study of 3077 participants found significant differences in gender, age, height, and weight across various Body Mass Index (BMI) categories. The study found non-significant variations in forced expiratory flow (FVC) across BMI categories, with underweight individuals showing lower FVC compared to normal and overweight individuals. BMI significantly impacted mean forced expiratory flow during the middle half of FVC. A significant negative correlation was observed between age and FVC, FEV1, FEV1/FVC ratio, and FEF25-75. A significant positive correlation was observed between weight, height, and lung function parameters. Multiple regression analysis revealed a decrease in lung function with advancing age, while height showed significant positive associations. The study concluded that age, sex, smoking, height, and weight collectively explained 41.0% of the variance in FVC, FEV, and FEF25-75.

摘要

目的

体重与健康之间的关系是一个重大的公共卫生关注点。虽然肥胖对肺功能的不良影响是众所周知的,但由于研究有限,体重过轻的影响仍存在争议。本研究旨在调查身体质量指数(BMI)类别与肺功能参数之间的相关性。

结果

对 3077 名参与者的研究发现,不同 BMI 类别在性别、年龄、身高和体重方面存在显著差异。研究发现,BMI 类别之间用力呼气流量(FVC)没有显著变化,与正常和超重个体相比,体重过轻的个体 FVC 较低。BMI 显著影响 FVC 中间一半的平均用力呼气流量。年龄与 FVC、FEV1、FEV1/FVC 比值和 FEF25-75 之间存在显著负相关。体重、身高与肺功能参数之间存在显著正相关。多元回归分析显示,随着年龄的增长,肺功能下降,而身高则显示出显著的正相关。研究得出结论,年龄、性别、吸烟、身高和体重共同解释了 FVC、FEV 和 FEF25-75 变异的 41.0%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/341d/11515375/02f9e20b9c3b/13104_2024_6967_Fig1_HTML.jpg

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