Wang Shengyu, Sun Xiuzhen, Hsia Te-Chun, Lin Xiaobo, Li Manxiang
Department of Respiratory Medicine, The First Affiliated Hospital of Xi'an Jiaotong University Department of Respiratory Medicine, The First Affiliated Hospital of Xi'an Medical University Department of Respiratory Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, PR China Department of Internal Medicine& Respiratory Therapy, China Medical University, Taichung, Taiwan.
Medicine (Baltimore). 2017 Apr;96(15):e6596. doi: 10.1097/MD.0000000000006596.
Obese people have higher risk of respiratory symptoms. The relationship between obesity and lung function varies with age, race, and geographical region. The objective of this study is to examine the effects of body mass index on spirometric tests among adults in Xi'an city.This is a cross-sectional study. Pulmonary function testing was conducted on participants recruited from Xi'an, China between July and August 2012. Force expiratory volume in first second (FEV1), force vital capacity (FVC), FEV1/FVC, peak expiratory flow (PEF), and forced expiratory flow at 25-75% (FEF25-75) were measured by portable Spirometer. Lung function was analyzed according to Chinese standard of general obesity.A total of 770 subjects were analyzed in this study, of whom 299 were males and 471 were females. FVC% (P = .037) decreased significantly in obese subjects than in nonobese subjects. FVC% (P = .02) declined significantly in overweight subjects than in normal subjects. For smoker, FEV1% (P = .03) and FVC% (P = .02) were lower notably in overweight subjects than in normal subjects. FEV1% (P = .0008), FVC% (P = .0004), and PEF% (P < .0001) were higher significantly in normal subjects than in underweight subjects.FVC notably decreased in obese people, not FEV1, FEV1/FVC, PEF, and FEF25-75. FEV1, FVC, and PEF were higher significantly in normal subjects than in underweight subjects. FVC is affected by BMI in diphasic change.
肥胖人群出现呼吸道症状的风险更高。肥胖与肺功能之间的关系因年龄、种族和地理区域而异。本研究的目的是探讨体重指数对西安市成年人肺量计测试的影响。
这是一项横断面研究。2012年7月至8月期间，对从中国西安招募的参与者进行了肺功能测试。使用便携式肺量计测量第一秒用力呼气量（FEV1）、用力肺活量（FVC）、FEV1/FVC、呼气峰值流速（PEF）以及25%-75%用力呼气流量（FEF25-75）。根据中国一般肥胖标准分析肺功能。
本研究共分析了770名受试者，其中男性299名，女性471名。肥胖受试者的FVC%（P = 0.037）较非肥胖受试者显著降低。超重受试者的FVC%（P = 0.02）较正常受试者显著下降。对于吸烟者，超重受试者的FEV1%（P = 0.03）和FVC%（P = 0.02）显著低于正常受试者。正常受试者的FEV1%（P = 0.0008）、FVC%（P = 0.0004）和PEF%（P < 0.0001）显著高于体重过轻的受试者。
肥胖人群的FVC显著降低，而FEV1、FEV1/FVC、PEF和FEF25-75则不然。正常受试者的FEV1、FVC和PEF显著高于体重过轻的受试者。FVC受BMI的影响呈双相变化。
