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2
Associations of timing of physical activity with all-cause and cause-specific mortality in a prospective cohort study.在一项前瞻性队列研究中,体力活动时间与全因和特定原因死亡率的关联。
Nat Commun. 2023 Feb 18;14(1):930. doi: 10.1038/s41467-023-36546-5.
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Smoothed Quantile Regression with Large-Scale Inference.具有大规模推断的平滑分位数回归
J Econom. 2023 Feb;232(2):367-388. doi: 10.1016/j.jeconom.2021.07.010. Epub 2021 Aug 24.
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Distributional data analysis via quantile functions and its application to modeling digital biomarkers of gait in Alzheimer's Disease.基于分位数函数的分布数据分析及其在阿尔茨海默病步态数字生物标志物建模中的应用。
Biostatistics. 2023 Jul 14;24(3):539-561. doi: 10.1093/biostatistics/kxab041.
5
Association of wearable device-measured vigorous intermittent lifestyle physical activity with mortality.可穿戴设备测量的剧烈间歇性生活方式体力活动与死亡率的关联。
Nat Med. 2022 Dec;28(12):2521-2529. doi: 10.1038/s41591-022-02100-x. Epub 2022 Dec 8.
6
Registration of 24-hour accelerometric rest-activity profiles and its application to human chronotypes.24小时加速度计静息-活动图谱的记录及其在人类昼夜节律类型中的应用。
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Fast Univariate Inference for Longitudinal Functional Models.纵向功能模型的快速单变量推断
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8
Quantile Function on Scalar Regression Analysis for Distributional Data.分布数据标量回归分析中的分位数函数
J Am Stat Assoc. 2020;115(529):90-106. doi: 10.1080/01621459.2019.1609969. Epub 2019 Jun 21.
9
Organizing and analyzing the activity data in NHANES.整理和分析美国国家健康与营养检查调查(NHANES)中的活动数据。
Stat Biosci. 2019 Jul;11(2):262-287. doi: 10.1007/s12561-018-09229-9. Epub 2019 Feb 9.
10
The Predictive Performance of Objective Measures of Physical Activity Derived From Accelerometry Data for 5-Year All-Cause Mortality in Older Adults: National Health and Nutritional Examination Survey 2003-2006.基于加速度计数据的体力活动客观测量指标对老年人 5 年全因死亡率的预测性能:2003-2006 年国家健康与营养调查。
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功能分位数主成分分析

Functional quantile principal component analysis.

作者信息

Méndez-Civieta Álvaro, Wei Ying, Diaz Keith M, Goldsmith Jeff

机构信息

Department of Biostatistics, Columbia University, 722W 178 St, New York, NY 10032, United States.

uc3m-Santander Big Data Institute, University Carlos III of Madrid, C. Madrid, 126, Madrid 28903, Spain.

出版信息

Biostatistics. 2024 Dec 31;26(1). doi: 10.1093/biostatistics/kxae040.

DOI:10.1093/biostatistics/kxae040
PMID:39449078
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11823270/
Abstract

This paper introduces functional quantile principal component analysis (FQPCA), a dimensionality reduction technique that extends the concept of functional principal components analysis (FPCA) to the examination of participant-specific quantiles curves. Our approach borrows strength across participants to estimate patterns in quantiles, and uses participant-level data to estimate loadings on those patterns. As a result, FQPCA is able to capture shifts in the scale and distribution of data that affect participant-level quantile curves, and is also a robust methodology suitable for dealing with outliers, heteroscedastic data or skewed data. The need for such methodology is exemplified by physical activity data collected using wearable devices. Participants often differ in the timing and intensity of physical activity behaviors, and capturing information beyond the participant-level expected value curves produced by FPCA is necessary for a robust quantification of diurnal patterns of activity. We illustrate our methods using accelerometer data from the National Health and Nutrition Examination Survey, and produce participant-level 10%, 50%, and 90% quantile curves over 24 h of activity. The proposed methodology is supported by simulation results, and is available as an R package.

摘要

本文介绍了功能分位数主成分分析(FQPCA),这是一种降维技术,它将功能主成分分析(FPCA)的概念扩展到对参与者特定分位数曲线的检验。我们的方法利用参与者之间的优势来估计分位数中的模式,并使用参与者层面的数据来估计这些模式上的载荷。因此,FQPCA能够捕捉影响参与者层面分位数曲线的数据尺度和分布的变化,并且也是一种适用于处理异常值、异方差数据或偏态数据的稳健方法。使用可穿戴设备收集的身体活动数据就体现了对这种方法的需求。参与者在身体活动行为的时间和强度上往往存在差异,对于活动昼夜模式的稳健量化而言,捕捉FPCA产生的参与者层面期望值曲线之外的信息是必要的。我们使用来自国家健康与营养检查调查的加速度计数据来说明我们的方法,并生成24小时活动期间参与者层面的10%、50%和90%分位数曲线。所提出的方法得到了模拟结果的支持,并且可以作为一个R包获取。