Mohaghegh Fatemeh, Khodashenas Zohre, Saber Mina, Sohrabi Haniyeh
Department of Dermatology, Skin Diseases, and Leishmaniasis Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Dermatology, Faculty of Medicine, Shahed University, Tehran, Iran.
Case Rep Dermatol. 2024 Oct 24;16(1):226-233. doi: 10.1159/000541695. eCollection 2024 Jan-Dec.
Lichen planus (LP) is a chronic inflammatory dermatosis that causes plaques and itchy papules on the skin, as well as erosion and ulcers in the mucous membranes. LP is characterized by a dense dermal T-cell infiltration. Perieccrine inflammation can be seen in a variety of dermatoses, but genuine lymphocyte permeation of the secretory coil or lymphocytic syringotropism is a rare sign that is typically seen in mycosis fungoides.
In this study, we present 2 uncommon instances of lymphocytic syringotropism in LP. Histopathological examination revealed dense T-cell infiltration and lymphocytic involvement of eccrine glands, confirming syringotropism.
Lymphocytic syringotropism is an uncommon finding in LP. Its presence broadens the histopathological spectrum of LP and highlights the need to differentiate it from lymphoproliferative disorders like mycosis fungoides.
扁平苔藓(LP)是一种慢性炎症性皮肤病,可导致皮肤出现斑块和瘙痒性丘疹,以及黏膜糜烂和溃疡。LP的特征是真皮层有密集的T细胞浸润。在多种皮肤病中都可见到汗腺周围炎症,但真正的分泌蟠管淋巴细胞浸润或淋巴细胞性汗腺趋向性是一种罕见表现,通常见于蕈样肉芽肿。
在本研究中,我们呈现了2例LP中罕见的淋巴细胞性汗腺趋向性病例。组织病理学检查显示有密集的T细胞浸润以及汗腺的淋巴细胞受累,证实了汗腺趋向性。
淋巴细胞性汗腺趋向性在LP中是一种罕见表现。它的出现拓宽了LP的组织病理学谱,并突出了将其与蕈样肉芽肿等淋巴增殖性疾病相鉴别的必要性。