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向心性扁平苔藓：一种常见皮肤病的不寻常表现——2例报告

Syringotropic Lichen Planus: An Unusual Presentation of a Common Dermatosis - A Report of 2 Cases.

作者信息

Mohaghegh Fatemeh, Khodashenas Zohre, Saber Mina, Sohrabi Haniyeh

机构信息

Department of Dermatology, Skin Diseases, and Leishmaniasis Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Department of Dermatology, Faculty of Medicine, Shahed University, Tehran, Iran.

出版信息

Case Rep Dermatol. 2024 Oct 24;16(1):226-233. doi: 10.1159/000541695. eCollection 2024 Jan-Dec.

DOI:10.1159/000541695
PMID:39449728
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11501101/
Abstract

INTRODUCTION

Lichen planus (LP) is a chronic inflammatory dermatosis that causes plaques and itchy papules on the skin, as well as erosion and ulcers in the mucous membranes. LP is characterized by a dense dermal T-cell infiltration. Perieccrine inflammation can be seen in a variety of dermatoses, but genuine lymphocyte permeation of the secretory coil or lymphocytic syringotropism is a rare sign that is typically seen in mycosis fungoides.

CASE PRESENTATION

In this study, we present 2 uncommon instances of lymphocytic syringotropism in LP. Histopathological examination revealed dense T-cell infiltration and lymphocytic involvement of eccrine glands, confirming syringotropism.

CONCLUSION

Lymphocytic syringotropism is an uncommon finding in LP. Its presence broadens the histopathological spectrum of LP and highlights the need to differentiate it from lymphoproliferative disorders like mycosis fungoides.

摘要

引言

扁平苔藓（LP）是一种慢性炎症性皮肤病，可导致皮肤出现斑块和瘙痒性丘疹，以及黏膜糜烂和溃疡。LP的特征是真皮层有密集的T细胞浸润。在多种皮肤病中都可见到汗腺周围炎症，但真正的分泌蟠管淋巴细胞浸润或淋巴细胞性汗腺趋向性是一种罕见表现，通常见于蕈样肉芽肿。

病例报告

在本研究中，我们呈现了2例LP中罕见的淋巴细胞性汗腺趋向性病例。组织病理学检查显示有密集的T细胞浸润以及汗腺的淋巴细胞受累，证实了汗腺趋向性。

结论

淋巴细胞性汗腺趋向性在LP中是一种罕见表现。它的出现拓宽了LP的组织病理学谱，并突出了将其与蕈样肉芽肿等淋巴增殖性疾病相鉴别的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/799f/11501101/e3baa6e16f03/cde-2024-0016-0001-541695_F05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/799f/11501101/76fa95366e1f/cde-2024-0016-0001-541695_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/799f/11501101/28c90ee8f1cf/cde-2024-0016-0001-541695_F02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/799f/11501101/98de8780e642/cde-2024-0016-0001-541695_F03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/799f/11501101/45c6ff70ea49/cde-2024-0016-0001-541695_F04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/799f/11501101/e3baa6e16f03/cde-2024-0016-0001-541695_F05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/799f/11501101/76fa95366e1f/cde-2024-0016-0001-541695_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/799f/11501101/28c90ee8f1cf/cde-2024-0016-0001-541695_F02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/799f/11501101/98de8780e642/cde-2024-0016-0001-541695_F03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/799f/11501101/45c6ff70ea49/cde-2024-0016-0001-541695_F04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/799f/11501101/e3baa6e16f03/cde-2024-0016-0001-541695_F05.jpg

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本文引用的文献

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J Drugs Dermatol. 2022 Dec 1;21(12):1362-1364. doi: 10.36849/JDD.6779.
2
Linear Systematized Porokeratosis-A Rare Case and Dermoscopic Clues to Diagnosis.线状系统性汗孔角化症——1例罕见病例及皮肤镜诊断线索
Indian Dermatol Online J. 2020 Sep 28;12(3):465-466. doi: 10.4103/idoj.IDOJ_419_20. eCollection 2021 May-Jun.
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Adnexotropic Variants of the Interface Dermatitides: A Review.
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Dermatopathology (Basel). 2021 May 21;8(2):135-146. doi: 10.3390/dermatopathology8020020.
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Lichen planopilaris in men: a retrospective clinicopathologic study of 19 patients.男性毛囊性扁平苔藓：19 例回顾性临床病理研究。
Int J Dermatol. 2021 Apr;60(4):482-488. doi: 10.1111/ijd.15285. Epub 2020 Oct 31.
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Dermoscopy in folliculotropic mycosis fungoides-A possible mimicker of follicle-based inflammatory and infectious disorders.毛囊性蕈样肉芽肿的皮肤镜检查——一种可能模仿毛囊性炎症和感染性疾病的情况。
J Am Acad Dermatol. 2019 Sep;81(3):e75-e76. doi: 10.1016/j.jaad.2019.04.063. Epub 2019 May 10.
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Direct Immunofluorescence Studies in Lichen Planus.扁平苔藓的直接免疫荧光研究
Turk Patoloji Derg. 2019;35(3):193-197. doi: 10.5146/tjpath.2018.01455.
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Syringotropic Lichen Planus: A Potential Histopathologic Mimicker of Syringotropic Mycosis Fungoides.向汗腺性扁平苔藓：一种可能在组织病理学上模仿向汗腺性蕈样肉芽肿的疾病。
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