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一项多中心回顾性病历审查研究:估算沙特阿拉伯利雅得婴幼儿及儿童缺铁性贫血的患病率

A Multicenter Retrospective Chart Review Study Estimating the Prevalence of Iron Deficiency Anemia Among Infants, Toddlers, and Children in Riyadh, Saudi Arabia.

作者信息

Almutairi Ahmed M, Alwehaibi Sultan A, Almousa Abdulaziz Y, Alanazi Salma, Bin Muaibed Rewaida R, Althobaiti Renad, Alkheraiji Abdulaziz M, Alamrani Haya A

机构信息

Pediatrics, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, SAU.

Medicine, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, SAU.

出版信息

Cureus. 2024 Sep 23;16(9):e70031. doi: 10.7759/cureus.70031. eCollection 2024 Sep.

Abstract

Background Iron deficiency anemia (IDA) is a prevalent nutritional disorder affecting children worldwide, leading to potential long-term cognitive and developmental deficits. This study aimed to determine the prevalence of IDA among healthy children attending Dr. Sulaiman Al-Habib Hospital Group in Riyadh, SAU, and explore the relationship between IDA and various demographic factors, including age, gender, and nationality. Methodology A retrospective chart review was conducted from July 2023 to August 2023 at Dr. Sulaiman Al-Habib Hospital Group, in Riyadh, Saudi Arabia. The study included 498 children aged 0.58 to 17 years, selected through a cluster sampling technique. Data on demographic characteristics and laboratory results, including hemoglobin (Hb) levels, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red cell distribution width (RDW), ferritin, and RBC, were collected. Iron deficiency anemia was diagnosed based on Hb levels and other hematological indices. Statistical analysis was performed using SPSS Statistics version 23.0 (IBM Corp., Armonk, NY, USA). Results The prevalence of IDA among the study population was 9.2%, with 72.3% of the cases classified as mild and 27.7% as moderate. No cases of severe anemia were found. Infants had the highest prevalence of IDA (16.9%), followed by toddlers (12.0%), preschool children (7.2%), and school-age children (0.8%). Gender analysis revealed a prevalence of 9.7% in males and 8.6% in females, with no significant difference between genders (p = 0.659). All non-Saudi participants were free of IDA, whereas 9.3% of Saudi participants had IDA, though this difference was not statistically significant (p = 0.761). Conclusion The study found a relatively low prevalence of IDA among healthy children attending Dr. Sulaiman Al-Habib Hospital Group in Riyadh, SAU, with the highest prevalence observed among infants. These findings highlight the need for targeted interventions to prevent IDA, particularly in younger children. Routine screening and early treatment are crucial to mitigate the potential long-term effects of IDA on child development. Further research with larger and more diverse samples is recommended to validate these findings and explore additional factors influencing IDA prevalence.

摘要

背景 缺铁性贫血(IDA)是一种普遍存在的营养失调症,影响着全球儿童,可能导致潜在的长期认知和发育缺陷。本研究旨在确定沙特阿拉伯利雅得市苏莱曼·哈比卜博士医院集团就诊的健康儿童中缺铁性贫血的患病率,并探讨缺铁性贫血与各种人口统计学因素之间的关系,包括年龄、性别和国籍。方法 2023年7月至2023年8月在沙特阿拉伯利雅得市苏莱曼·哈比卜博士医院集团进行了一项回顾性病历审查。该研究纳入了498名年龄在0.58至17岁之间的儿童,通过整群抽样技术选取。收集了人口统计学特征和实验室结果的数据,包括血红蛋白(Hb)水平、平均红细胞体积(MCV)、平均红细胞血红蛋白(MCH)、平均红细胞血红蛋白浓度(MCHC)、红细胞分布宽度(RDW)、铁蛋白和红细胞(RBC)。根据Hb水平和其他血液学指标诊断缺铁性贫血。使用SPSS Statistics 23.0版(美国纽约州阿蒙克市IBM公司)进行统计分析。结果 研究人群中缺铁性贫血的患病率为9.2%,其中72.3%的病例被归类为轻度,27.7%为中度。未发现重度贫血病例。婴儿缺铁性贫血的患病率最高(16.9%),其次是幼儿(12.0%)、学龄前儿童(7.2%)和学龄儿童(0.8%)。性别分析显示,男性患病率为9.7%,女性患病率为8.6%,性别之间无显著差异(p = 0.659)。所有非沙特参与者均无缺铁性贫血,而9.3%的沙特参与者患有缺铁性贫血,尽管这一差异无统计学意义(p = 0.761)。结论 该研究发现,沙特阿拉伯利雅得市苏莱曼·哈比卜博士医院集团就诊的健康儿童中缺铁性贫血的患病率相对较低,婴儿患病率最高。这些发现凸显了采取针对性干预措施预防缺铁性贫血的必要性,特别是在年幼儿童中。常规筛查和早期治疗对于减轻缺铁性贫血对儿童发育的潜在长期影响至关重要。建议进行更大规模和更多样化样本的进一步研究,以验证这些发现并探索影响缺铁性贫血患病率的其他因素。

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