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内脏利什曼病中的噬血细胞性淋巴组织细胞增生症:一种罕见但可治疗的并发症。

Hemophagocytic Lymphohistiocytosis in Visceral Leishmaniasis: A Rare yet Treatable Complication.

作者信息

Varshney Anupam, Solanki Ranjan, Manna David, Rodriguez Efren, Bindra Vijay K

机构信息

Department of Pathology, Muzaffarnagar Medical College and Hospital, Muzaffarnagar, IND.

Department of Basic Biomedical Sciences, Touro College of Osteopathic Medicine, Middletown, USA.

出版信息

Cureus. 2024 Sep 24;16(9):e70104. doi: 10.7759/cureus.70104. eCollection 2024 Sep.

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a rare debilitating condition that can be triggered by an infectious cause, often linked to the Epstein-Barr virus (EBV). In this case, we evaluated a patient with pancytopenia. The bone marrow aspiration revealed the presence of amastigotes and active hemophagocytosis, indicating that the HLH was induced by a infection. The patient was treated with lyophilized amphotericin B followed by miltefosine, which effectively resolved the infection and HLH. This case report underscores the presentation and findings of -induced HLH, as well as the successful treatment approach that led to improved patient outcomes.

摘要

噬血细胞性淋巴组织细胞增生症(HLH)是一种罕见的使人衰弱的病症,可由感染因素引发,通常与爱泼斯坦-巴尔病毒(EBV)有关。在本病例中,我们评估了一名全血细胞减少症患者。骨髓穿刺显示存在无鞭毛体和活跃的噬血细胞现象,表明HLH是由感染引起的。该患者接受了冻干两性霉素B治疗,随后使用米替福新,有效解决了感染和HLH问题。本病例报告强调了感染诱发的HLH的表现和发现,以及导致患者预后改善的成功治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7c7/11501513/8466fdbbb165/cureus-0016-00000070104-i01.jpg

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