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一名患有神经介导性完全性心脏传导阻滞和晕厥的儿科患者起搏器治疗失败：病例报告

Failure of pacemaker therapy in a pediatric patient with neurally mediated complete heart block and syncope: A case report.

作者信息

Dalili Mohammad, Rahimpoor Feisal

机构信息

Rajaie Cardiovascular Medical & Research Center Iran University of Medical Sciences Tehran Iran.

Mashhad Cardiovascular Medical & Research Center Mashhad Iran.

出版信息

Clin Case Rep. 2024 Oct 23;12(10):e9527. doi: 10.1002/ccr3.9527. eCollection 2024 Oct.

DOI:10.1002/ccr3.9527
PMID:39450200
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11499065/
Abstract

Neurally mediated syncope (NMS) is a well-known condition that can be subdivided into three subgroups: vasopressor type, cardioinhibitory type, and mixed type. While different degrees of sinus bradycardia occur at the time of syncope in all types, complete heart block is a rare event that can lead to pulselessness during syncope. We present a case of a 14-year-old girl with documented NMS before and after temporary pacemaker implantation, who had complete heart block during syncope. The patient's temporary pacemaker placement was ineffective in preventing syncope during a repeat head-up tilt test, indicating that permanent pacing may not be effective in this patient. Midodrine, an alpha-adrenergic agonist, was started, and the patient experienced complete control of syncope episodes without recurrence during a 2-month follow-up.

摘要

神经介导性晕厥（NMS）是一种众所周知的病症，可细分为三个亚组：血管加压素型、心脏抑制型和混合型。虽然在所有类型的晕厥发作时都会出现不同程度的窦性心动过缓，但完全性心脏传导阻滞是一种罕见事件，可导致晕厥时脉搏消失。我们报告一例14岁女孩，在临时起搏器植入前后均确诊为NMS，其在晕厥时发生了完全性心脏传导阻滞。在重复的头高位倾斜试验中，患者的临时起搏器置入未能有效预防晕厥，这表明永久性起搏对该患者可能无效。于是开始使用α-肾上腺素能激动剂米多君，在2个月的随访期间，患者的晕厥发作得到完全控制，未再复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c2/11499065/6e6b2fe33cc2/CCR3-12-e9527-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c2/11499065/e332c7a1c8e8/CCR3-12-e9527-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c2/11499065/6e6b2fe33cc2/CCR3-12-e9527-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c2/11499065/e332c7a1c8e8/CCR3-12-e9527-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c2/11499065/6e6b2fe33cc2/CCR3-12-e9527-g001.jpg

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本文引用的文献

1
2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy.2021年欧洲心脏病学会心脏起搏与心脏再同步治疗指南。
Eur Heart J. 2021 Sep 14;42(35):3427-3520. doi: 10.1093/eurheartj/ehab364.
2
New insights in diagnostics and therapies in syncope: a novel approach to non-cardiac syncope.晕厥的诊断和治疗新视角：非心源性晕厥的新方法。
Heart. 2021 Jun;107(11):864-873. doi: 10.1136/heartjnl-2020-318261. Epub 2021 Jan 18.
3
2018 ESC Guidelines for the diagnosis and management of syncope.2018年欧洲心脏病学会晕厥诊断和管理指南。
Eur Heart J. 2018 Jun 1;39(21):1883-1948. doi: 10.1093/eurheartj/ehy037.
4
2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.2017年美国心脏病学会/美国心脏协会/美国心律学会晕厥患者评估与管理指南：执行摘要：美国心脏病学会/美国心脏协会临床实践指南工作组及心律学会报告
J Am Coll Cardiol. 2017 Aug 1;70(5):620-663. doi: 10.1016/j.jacc.2017.03.002. Epub 2017 Mar 9.
5
2015 heart rhythm society expert consensus statement on the diagnosis and treatment of postural tachycardia syndrome, inappropriate sinus tachycardia, and vasovagal syncope.2015年心律协会关于体位性心动过速综合征、不适当窦性心动过速和血管迷走性晕厥诊断与治疗的专家共识声明
Heart Rhythm. 2015 Jun;12(6):e41-63. doi: 10.1016/j.hrthm.2015.03.029. Epub 2015 May 14.
6
Epidemiology of syncope/collapse in younger and older Western patient populations.年轻和老年西方患者人群中晕厥/昏倒的流行病学。
Prog Cardiovasc Dis. 2013 Jan-Feb;55(4):357-63. doi: 10.1016/j.pcad.2012.11.006.
7
Guidelines for the diagnosis and management of syncope (version 2009).晕厥诊断与处理指南（2009年版）
Eur Heart J. 2009 Nov;30(21):2631-71. doi: 10.1093/eurheartj/ehp298. Epub 2009 Aug 27.
8
Syncopal high-degree AV block treated with catheter RF ablation without pacemaker implantation.经导管射频消融治疗的晕厥性高度房室传导阻滞，未植入起搏器。
Pacing Clin Electrophysiol. 2006 Mar;29(3):318-22. doi: 10.1111/j.1540-8159.2006.00340.x.
9
"Cardioneuroablation"--new treatment for neurocardiogenic syncope, functional AV block and sinus dysfunction using catheter RF-ablation.“心脏神经消融术”——一种使用导管射频消融术治疗神经心源性晕厥、功能性房室传导阻滞和窦房结功能障碍的新疗法。
Europace. 2005 Jan;7(1):1-13. doi: 10.1016/j.eupc.2004.10.003.
10
Guidelines on management (diagnosis and treatment) of syncope--update 2004.晕厥管理（诊断与治疗）指南——2004年更新版
Europace. 2004 Nov;6(6):467-537. doi: 10.1016/j.eupc.2004.08.008.