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韩国自然感染猴痘病毒与接种猴痘疫苗6个月后抗体反应减弱情况的比较

Comparison of Waning Antibody Responses After Natural Monkeypox Virus Infection and Mpox Vaccination Beyond 6 Months in South Korea.

作者信息

Lim So Yun, Kim Hyang Su, Yim Hong Soon, Kim Hyesu, Han In Ae, Yoon Doran, Kim Min-Kyung, Kim Yeonjae, Um Jihye, Kim Gayeon, Chin BumSik, Park Jun-Sun, Bang Jihwan

机构信息

Division of Infectious Diseases, Department of Internal Medicine, National Medical Center, Seoul, Republic of Korea.

Public Health Research Institute, National Medical Center, Seoul, Republic of Korea.

出版信息

Open Forum Infect Dis. 2024 Oct 5;11(10):ofae566. doi: 10.1093/ofid/ofae566. eCollection 2024 Oct.

Abstract

Natural Monkeypox virus infection induced significantly higher neutralizing antibody titers than Jynneos vaccination, with similar antibody decay rates beyond 6 months. Jynneos recipients with prior smallpox vaccination showed antibody levels comparable to mpox convalescents.

摘要

自然感染猴痘病毒诱导产生的中和抗体滴度显著高于接种Jynneos疫苗,6个月后抗体衰减率相似。既往接种过天花疫苗的Jynneos疫苗接种者的抗体水平与猴痘康复者相当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2c9/11500191/431969f129cb/ofae566f1.jpg

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