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基于定性研究的乳腺癌内分泌治疗患者体验:患者就医历程图

The Experience of Patients with Endocrine Therapy for Breast Cancer: A Patient Journey Map Based on Qualitative Research.

机构信息

School of Nursing, Jinan University, Guangzhou 510632, China.

Guangzhou Chest Hospital, Guangzhou 510095, China.

出版信息

Curr Oncol. 2024 Sep 30;31(10):5873-5888. doi: 10.3390/curroncol31100437.

DOI:10.3390/curroncol31100437
PMID:39451741
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11506757/
Abstract

(1) Background: While there is extensive documentation on the medical experience of breast cancer, a thorough understanding of the various stages of endocrine therapy remains insufficient. The aim of this study was to map the experiences and coping styles of breast cancer patients during endocrine therapy. (2) Methods: Qualitative research was conducted to gather insights into the experiences of breast cancer patients undergoing endocrine therapy. The themes were organized through content analysis and induction. Subsequently, patients were invited for face-to-face interviews at a top-three hospital in Guangzhou to supplement and validate the findings from the literature review. The patient journey was then mapped based on both the literature review and the semi-structured interviews. (3) Results: A total of 24 studies were included that described patients' experiences and behaviors during the early, middle, and late stages of treatment, leading to the formation of a preliminary framework. Interviews were conducted with 20 patients, which confirmed and enriched the findings from the literature review. Based on these results, a stage trajectory for endocrine therapy in breast cancer was established. (4) Conclusions: The patient journey map developed in this study clearly and intuitively illustrates the thought and emotion matrix, as well as the behavior matrix, of breast cancer patients undergoing endocrine therapy. This provides a theoretical foundation for enhancing clinical services tailored to the needs of these patients.

摘要

(1) 背景:尽管有大量关于乳腺癌医学经验的文献,但对内分泌治疗各个阶段的全面理解仍显不足。本研究旨在绘制乳腺癌患者在内分泌治疗期间的体验和应对方式图。(2) 方法:为深入了解接受内分泌治疗的乳腺癌患者的体验,采用定性研究方法。通过内容分析和归纳对主题进行组织。随后,邀请患者在广州三甲医院进行面对面访谈,以补充和验证文献综述中的发现。根据文献综述和半结构化访谈结果,绘制患者的治疗旅程图。(3) 结果:共纳入 24 项研究,描述了患者在治疗早期、中期和晚期的体验和行为,从而形成了一个初步的框架。对 20 名患者进行了访谈,证实并丰富了文献综述的结果。基于这些结果,建立了乳腺癌内分泌治疗的阶段轨迹。(4) 结论:本研究绘制的患者治疗旅程图清晰直观地展示了乳腺癌患者在内分泌治疗过程中的思维和情感矩阵以及行为矩阵,为增强针对这些患者需求的临床服务提供了理论基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eeb/11506757/71a2dee83858/curroncol-31-00437-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eeb/11506757/3848114f6862/curroncol-31-00437-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eeb/11506757/71a2dee83858/curroncol-31-00437-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eeb/11506757/3848114f6862/curroncol-31-00437-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eeb/11506757/71a2dee83858/curroncol-31-00437-g002.jpg

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本文引用的文献

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Challenges in Obtaining and Seeking Information Among Breast Cancer Survivors in an Asian Country: a Qualitative Study.亚洲国家乳腺癌幸存者获取和寻求信息的挑战:一项定性研究。
J Cancer Educ. 2024 Aug;39(4):383-390. doi: 10.1007/s13187-024-02421-0. Epub 2024 Mar 26.
2
Symptoms and need for individualised support during the first year after primary treatment for breast cancer-A qualitative study.乳腺癌初级治疗后第一年的症状和个体化支持需求:一项定性研究。
J Clin Nurs. 2024 Jun;33(6):2298-2308. doi: 10.1111/jocn.17045. Epub 2024 Feb 2.
3
The lived experience of patients with breast cancer on adjuvant endocrine therapy: side effects and coping strategies during the first year of medication initiation.
乳腺癌患者辅助内分泌治疗的生活体验:药物起始治疗第一年的副作用和应对策略。
Support Care Cancer. 2023 Nov 27;31(12):719. doi: 10.1007/s00520-023-08170-y.
4
Estrogen deprivation effects of endocrine therapy in breast cancer patients: Incidence, management and outcome.内分泌治疗对乳腺癌患者雌激素剥夺的影响:发生率、管理和结局。
Cancer Treat Rev. 2023 Nov;120:102624. doi: 10.1016/j.ctrv.2023.102624. Epub 2023 Sep 7.
5
Systemic therapy for hormone receptor-positive/human epidermal growth factor receptor 2-negative early stage and metastatic breast cancer.激素受体阳性/人表皮生长因子受体 2 阴性早期和转移性乳腺癌的全身治疗。
CA Cancer J Clin. 2023 Sep-Oct;73(5):480-515. doi: 10.3322/caac.21777. Epub 2023 Mar 20.
6
Facing points of view: Representations on adjuvant endocrine therapy of premenopausal patients after breast cancer and their healthcare providers in France. The FOR-AD study.面对观点:法国乳腺癌绝经前患者辅助内分泌治疗的代表性研究及其医疗保健提供者。FOR-AD 研究。
Eur J Oncol Nurs. 2023 Feb;62:102259. doi: 10.1016/j.ejon.2022.102259. Epub 2022 Dec 27.
7
Hobson's choice or a horned dilemma: a grounded theory on adherence to adjuvant endocrine therapy verified with breast cancer survivors.别无选择或进退两难:一项经乳腺癌幸存者验证的辅助内分泌治疗依从性的扎根理论。
Support Care Cancer. 2022 Dec;30(12):10127-10136. doi: 10.1007/s00520-022-07435-2. Epub 2022 Nov 7.
8
Breast cancer: presentation, investigation and management.乳腺癌:临床表现、检查及处理。
Br J Hosp Med (Lond). 2022 Feb 2;83(2):1-7. doi: 10.12968/hmed.2021.0459. Epub 2022 Feb 7.
9
Both "Vitamin L for Life" and "One Milligram of Satan": A Multi-Perspective Qualitative Exploration of Adjuvant Endocrine Therapy Use after Breast Cancer.《生命的维生素 L》和《一毫克撒旦》:乳腺癌辅助内分泌治疗使用的多视角定性探索。
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Extending Adjuvant Endocrine Therapy for 10 Years: A Mixed-Methods Analysis of Women's Decision Making in an Online Breast Cancer Forum.延长辅助内分泌治疗至10年:在线乳腺癌论坛中女性决策的混合方法分析
Healthcare (Basel). 2021 Jun 7;9(6):688. doi: 10.3390/healthcare9060688.