Kawasaki Yuko, Sudo Tamotsu, Tamura Kazuo, Hinoshita Saki, Hasuoka Kayoko, Miyawaki Satoko, Matsutani Nao, Hirasawa Akira, Uchinuno Atsuko
College of Nursing Art and Science, University of Hyogo, Akashi 673-8588, Japan.
Department of Cancer Genomics, Fujita Health University Hospital, Toyoake 47-1192, Japan.
Clin Pract. 2024 Oct 12;14(5):2105-2115. doi: 10.3390/clinpract14050166.
(1) Background: The number of patients with cancer undergoing cancer genome profiling is increasing; however, it remains unclear how accurately they understand the details of the tests and treatments. This study aimed to clarify the awareness of cancer genome profiling tests among patients with cancer who visited cancer genome medical clinics. (2) Methods: A questionnaire survey was conducted on awareness, anxiety, sources of information, and psychological states concerning cancer genome profiling tests. (3) Results: In total, 265 patients with cancer (117 men, 142 women, 6 no response, average age of 58.29 ± 11.9 years) were included in the study, of which 218 (82.3%) were aware of the term "cancer genomic medicine" and 90 (34.0%) were aware of its details. Thus, only a few respondents understood that cancer genome profiling tests facilitate the discovery of secondary findings and of genes associated with hereditary tumors. Regarding their psychological state when visiting the cancer genome clinic, the respondents were anxious about standard treatment and prognosis limits. (4) Conclusions: From the viewpoint of advance care planning, we suggest that medical professionals build a support system that links palliative care and cancer treatment and coordinates genetic counseling at an early stage.
(1) 背景：接受癌症基因组分析的癌症患者数量不断增加；然而，他们对检测和治疗细节的理解究竟有多准确仍不清楚。本研究旨在阐明前往癌症基因组医疗诊所的癌症患者对癌症基因组分析检测的认知情况。(2) 方法：针对癌症基因组分析检测的认知、焦虑、信息来源和心理状态进行了问卷调查。(3) 结果：本研究共纳入265例癌症患者（117例男性，142例女性，6例无回应，平均年龄58.29±11.9岁），其中218例（82.3%）知晓“癌症基因组医学”一词，90例（34.0%）了解其细节。因此，只有少数受访者明白癌症基因组分析检测有助于发现次要发现以及与遗传性肿瘤相关的基因。关于他们前往癌症基因组诊所时的心理状态，受访者对标准治疗和预后局限性感到焦虑。(4) 结论：从预先护理计划的角度来看，我们建议医疗专业人员建立一个将姑息治疗与癌症治疗联系起来并在早期协调遗传咨询的支持系统。
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