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用于放射治疗假体的3D打印牙科树脂和传统热固化牙科树脂的辐射防护性能评估

Radioprotection Performance Evaluation of 3D-Printed and Conventional Heat-Cured Dental Resins for Radiotherapy Prostheses.

作者信息

Wang Jiangyu, Murase Mai, Sumita Yuka I, Notake Ryoichi, Akiyama Masako, Yoshimura Ryoichi, Wakabayashi Noriyuki

机构信息

Department of Advanced Prosthodontics, Graduate School, Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 1138510, Japan.

Department of Partial and Complete Denture, The Nippon Dental University School of Life Dentistry, Tokyo 1028159, Japan.

出版信息

J Funct Biomater. 2024 Sep 25;15(10):282. doi: 10.3390/jfb15100282.

Abstract

3D printing is increasingly used in dentistry, with biocompatible resins playing a key role. This study compared the radioprotective properties of a commonly used 3D-printed resin (Formlabs surgical guide resin) with traditional heat-cured resin and examined the relationship between material thickness and radiation attenuation. The specimens consisted of 3D-printed and heat-cured resin specimens, each measuring 45 × 45 mm, with five different thicknesses (6, 8, 10, 12, and 14 mm), totaling 100 samples. Both types of resin specimens underwent testing with 150 MU external beam radiation therapy (EBRT) and 400 cGy brachytherapy. Radiation experiments indicated that under EBRT conditions, there were no significant differences in radiation attenuation between the 3D-printed and heat-cured resins across all thickness groups. In brachytherapy, the attenuation of the 3D-printed resin was significantly lower than the heat-cured resin in the 6 mm and 8 mm groups. Specifically, attenuation rates were 48.0 ± 0.7 (3D-printed) vs. 45.2 ± 1.9 (heat-cured) in the 6 mm group, and 39.6 ± 1.3 vs. 37.5 ± 1.1 in the 8 mm group. Both resins showed significant positive linear correlations between thickness and attenuation ( < 0.001) within 6-14 mm. Thus, 3D-printed resin shows promising radioprotective properties and is a viable alternative to traditional heat-cured resin.

摘要

3D打印在牙科领域的应用日益广泛,生物相容性树脂发挥着关键作用。本研究比较了一种常用的3D打印树脂(Formlabs手术导板树脂)与传统热固化树脂的辐射防护性能,并研究了材料厚度与辐射衰减之间的关系。标本包括3D打印和热固化树脂标本,每个标本尺寸为45×45毫米,有五种不同厚度(6、8、10、12和14毫米),共100个样本。两种类型的树脂标本都接受了150 MU外照射放疗(EBRT)和400 cGy近距离放疗测试。辐射实验表明,在EBRT条件下,所有厚度组的3D打印树脂和热固化树脂在辐射衰减方面没有显著差异。在近距离放疗中,3D打印树脂在6毫米和8毫米组中的衰减明显低于热固化树脂。具体而言,6毫米组的衰减率分别为48.0±0.7(3D打印)和45.2±1.9(热固化),8毫米组为39.6±1.3和37.5±1.1。在6 - 14毫米范围内,两种树脂的厚度与衰减之间均呈现显著的正线性相关性(<0.001)。因此,3D打印树脂显示出良好的辐射防护性能,是传统热固化树脂的可行替代品。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ba8/11508738/01721b460a01/jfb-15-00282-g001.jpg

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