Wang Hongmei, Guinn Dominique, Ramisetty Xavier Roshitha, Giordano Thomas P, Poon Ivy O
College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX 77004, USA.
Department of Pharmacy, Houston Methodist Hospital, Houston, TX 77030, USA.
Pharmacy (Basel). 2024 Sep 24;12(5):144. doi: 10.3390/pharmacy12050144.
Community pharmacies have unparalleled potential to increase access to pre-exposure prophylaxis medications (PrEP) for HIV prevention; however, only 17 out of 50 states in the United States have statewide authority for pharmacists to provide PrEP at community pharmacies. Few studies have reported on how pharmacists overcome the legislative barrier and provide PrEP services in restrictive pharmacy prescription states. The objective of this article is to identify the existing primary literature describing pharmacist PrEP services in the community in states with restrictive prescription authority.
A systemic literature review was conducted to identify the primary literature that involved community pharmacy service and PrEP conducted in states that do not have expanded pharmacist prescriptive authority between 2000 to 2024.
Ten publications were identified, describing nine studies, including four interview and survey studies, three intervention reports, and two ongoing clinical trials. None of these studies have a control group. Most pharmacists provide PrEP services in the community through a collaborative practice agreement with a primary care provider.
Future clinical studies with randomized controlled designs are required to test novel strategies in the education and implementation of pharmacy-led PrEP services in a community pharmacy setting to increase PrEP access.
社区药房在增加获得用于预防艾滋病毒的暴露前预防药物（PrEP）方面具有无与伦比的潜力；然而，在美国50个州中，只有17个州赋予药剂师在社区药房提供PrEP的全州范围权力。很少有研究报道药剂师如何克服立法障碍并在处方权限受限的药房提供PrEP服务。本文的目的是识别描述在处方权限受限的州社区中药剂师PrEP服务的现有主要文献。
进行了一项系统的文献综述，以识别2000年至2024年间在药剂师处方权限未扩大的州开展的涉及社区药房服务和PrEP的主要文献。
共识别出10篇出版物，描述了9项研究，包括4项访谈和调查研究、3份干预报告以及2项正在进行的临床试验。这些研究均无对照组。大多数药剂师通过与初级保健提供者签订合作实践协议在社区提供PrEP服务。
未来需要进行随机对照设计的临床研究，以测试在社区药房环境中开展由药房主导的PrEP服务的教育和实施方面的新策略，以增加PrEP的可及性。
