Diallo Mohamed Ciré, Kourouma Karifa, Boumbaly Saidou, Kamano Armand Saloun, Sow Abdoulaye, Grovogui Fassou Mathias, Traore Sahar, Delamou Alexandre
Institut de Recherche en Biologie Appliquée de Guinée (IRBAG), Kindia 00224, Guinea.
Centre National de Formation et de Recherche en Santé Rurale de Maferinyah (CNFRSR), Maferinyah, Forécariah B.P. 2649, Guinea.
Trop Med Infect Dis. 2024 Oct 11;9(10):238. doi: 10.3390/tropicalmed9100238.
The aim of this study was to describe the frequency, clinical signs, management, and outcomes of snakebite patients admitted to the envenomation treatment center of the Institut de Recherche en Biologie Appliquée de Guinée (IRBAG). This was a retrospective review combining aggregated annual statistics (2011-2015) and routine data (from January to October 2021) from the IRBAG treatment center. There were 1345 (57.2%) snakebite victims out of a total of 2352 consultations at the center during the study period. Males (67.7%), persons aged ≥45 years (29%) and ≤14 years (27.7%), farmers/housewives (44.5%), workers (23.9%), and those residing in the Kindia Prefecture (53.5%) were the most commonly affected. The majority of victims (84.5%) were admitted three hours after snakebite, with bites mainly occurring in rural areas (86.5%) and during the rainy season (83.2%). Pain (100%), edema (76.8%), and bleeding (65.2%) were the most common clinical presentations. Almost all victims received antivenom serum (98%), antibiotics (87.7%), and analgesics or anti-inflammatory drugs (88.4%). Six out of the one hundred and fifty-five patients died. Snakebites are a frequent public health problem in rural Guinea. The majority of victims seek medical attention too late. There is an urgent need to include snakebite in the country's list of priority NTDs in order to promote access to antivenom serum.
本研究的目的是描述被送往几内亚应用生物学研究所（IRBAG）蛇伤治疗中心的蛇咬伤患者的频率、临床症状、治疗及预后情况。这是一项回顾性研究，结合了IRBAG治疗中心的年度汇总统计数据（2011 - 2015年）和常规数据（2021年1月至10月）。在研究期间，该中心总共2352次会诊中有1345名（57.2%）蛇咬伤受害者。男性（67.7%）、年龄≥45岁（29%）和≤14岁（27.7%）的人群、农民/家庭主妇（44.5%）、工人（23.9%）以及居住在金迪亚省（53.5%）的人是受影响最普遍的群体。大多数受害者（84.5%）在被蛇咬后三小时入院，咬伤主要发生在农村地区（86.5%）和雨季（83.2%）。疼痛（100%）、水肿（76.8%）和出血（65.2%）是最常见的临床表现。几乎所有受害者都接受了抗蛇毒血清（98%）、抗生素（87.7%）以及镇痛药或抗炎药（88.4%）。155名患者中有6人死亡。蛇咬伤在几内亚农村是一个常见的公共卫生问题。大多数受害者寻求医疗救治太晚。迫切需要将蛇咬伤纳入该国重点被忽视热带病清单，以促进抗蛇毒血清的可及性。
