Vanherweghem J L, Dhaene M, Goldman M, Stolear J C, Sabot J P, Waterlot Y, Serruys E, Thayse C
Nephron. 1986;42(2):116-9. doi: 10.1159/000183648.
Two hundred subclavian dialysis catheters were placed in 148 patients who kept them in place for a total of 2,798 days. Catheterization time ranged from 1 to 79 days with an average of 14.0 +/- 1.0 days per catheter and 18.9 +/- 1.0 days per patient. Twenty nine catheters were infected, 17 of which were the source of bacteremias due to Staphylococcus epidermidis in 13 cases and to Staphylococcus aureus in 4 cases. The incidence of sepsis was not significantly greater in diabetic patients, in patients with corticotherapy or in patients presenting an underlying systemic disease. On the contrary, the incidence was greater in hospitalized patients (15 bacteremias during 1,948 catheter days) than in ambulatory patients (2 bacteremias during 850 catheters-days) as well as during a period corresponding to a greater number of untrained nurses enrolled in the dialysis team. During this period, 6 sepsies occurred in 19 catheters (other periods: 7 sepsies/116 catheters, p less than 0.01). 6 of 28 nurses had less than 3 months of professional experience (other periods: 1 of 25, p less than 0.01). These data underline the key role of nurse training in the prevention of catheter-related infections.
在148例患者中置入了200根锁骨下透析导管,这些患者共保留导管2798天。置管时间为1至79天,每根导管平均为14.0±1.0天,每名患者平均为18.9±1.0天。29根导管发生感染,其中17根是菌血症的来源,13例由表皮葡萄球菌引起,4例由金黄色葡萄球菌引起。糖尿病患者、接受皮质激素治疗的患者或患有基础系统性疾病的患者中,败血症的发生率并无显著增加。相反,住院患者(1948个导管日期间发生15次菌血症)的发生率高于门诊患者(850个导管日期间发生2次菌血症),在透析团队中未受过培训的护士人数较多的时期也是如此。在此期间,19根导管发生了6次败血症(其他时期:116根导管发生7次败血症,p<0.01)。28名护士中有6名专业经验不足3个月(其他时期:25名中有1名,p<0.01)。这些数据强调了护士培训在预防导管相关感染中的关键作用。