ECHO Laboratory, <a href="https://ror.org/02s376052">École Polytechnique Fédérale de Lausanne</a>, Lausanne, Switzerland.
<a href="https://ror.org/01bf9rw71">Max Planck Institute for the Physics of Complex Systems</a>, Dresden, Germany.
Phys Rev Lett. 2024 Oct 11;133(15):158401. doi: 10.1103/PhysRevLett.133.158401.
Biological and living organisms sense and process information from their surroundings, typically having access only to a subset of external observables for a limited amount of time. In this Letter, we uncover how biological systems can exploit these accessible degrees of freedom to transduce information from the inaccessible ones with a limited energy budget. We find that optimal transduction strategies may boost information harvesting over the ideal case in which all degrees of freedom are known, even when only finite-time trajectories are observed, at the price of higher dissipation. We apply our results to red blood cells, inferring the implemented transduction strategy from membrane flickering data and shedding light on the connection between mechanical stress and transduction efficiency. Our framework offers novel insights into the adaptive strategies of biological systems under nonequilibrium conditions.
生物和生命体从周围环境中感知和处理信息，通常只能在有限的时间内访问外部可观察量的一个子集。在这封信中，我们揭示了生物系统如何利用这些可访问的自由度，在能量预算有限的情况下，将信息从不可访问的自由度中转换出来。我们发现，即使只观察到有限时间的轨迹，最优的转换策略也可以提高信息采集的效率，超过所有自由度都已知的理想情况，代价是更高的耗散。我们将我们的结果应用于红细胞，从膜闪烁数据中推断出所采用的转换策略，并揭示了机械应力与转换效率之间的联系。我们的框架为非平衡条件下生物系统的自适应策略提供了新的见解。
