Buyukeren Melek, Ozcan Beyza, Can Ummugulsum, Kenar Aytac, Kececi Ramazan, Bayman Melike Geyik, Gunenc Oguzhan
Department of Pediatrics, Division of Neonatology, Konya City Hospital, Konya, Türkiye.
Department of Biochemistry, Konya City Hospital, Konya, Türkiye.
J Perinat Med. 2024 Oct 28;53(1):110-116. doi: 10.1515/jpm-2024-0236. Print 2025 Jan 29.
To compare the cord blood alarin levels of infants in different birth weight groups with those of infants born to mothers diagnosed with gestational diabetes mellitus (GDM) who were not subgrouped according to birth weight.
This prospective study was conducted between September 2023 and January 2024. Healthy term babies whose families agreed to participate in the study were divided into four groups according to their birth weight (small for gestational age (SGA), appropriate for gestational age (AGA) and large for gestational age (LGA)) and whether their mothers had GDM.
There was a significant difference between the cord blood alarin levels of the AGA and SGA groups (p=0.014). There was also a significant difference between the cord blood alarin levels of the AGA and GDM groups (p=0.012). However, the cord blood alarin levels of the LGA group (whose mothers did not have GDM) were similar to those of the AGA group (p=0.394).
We found evidence that alarin levels in umbilical cord blood are associated with low birth weight and GDM.
比较不同出生体重组婴儿的脐血阿拉辛水平与母亲被诊断为妊娠期糖尿病(GDM)但未按出生体重分组的婴儿的脐血阿拉辛水平。
本前瞻性研究于2023年9月至2024年1月进行。其家庭同意参与研究的足月健康婴儿根据出生体重(小于胎龄儿(SGA)、适于胎龄儿(AGA)和大于胎龄儿(LGA))以及其母亲是否患有GDM分为四组。
AGA组和SGA组的脐血阿拉辛水平存在显著差异(p = 0.014)。AGA组和GDM组的脐血阿拉辛水平也存在显著差异(p = 0.012)。然而,LGA组(其母亲没有GDM)的脐血阿拉辛水平与AGA组相似(p = 0.394)。
我们发现证据表明脐血中的阿拉辛水平与低出生体重和GDM有关。