Baker C H, Davis D L, Sutton E T
Proc Soc Exp Biol Med. 1986 Mar;181(3):338-44. doi: 10.3181/00379727-181-42262.
The innervation of the vasculature of the dog hindpaw separately controls the series and parallel coupled vessels by means of the tibial, deep fibular, and superficial fibular nerves. The latter primarily affects veins. The venous effects of the tibial and deep fibular nerves have not been adequately defined. The right hindpaw of anesthetized dogs was vascularly and neurally isolated in a volume recorder. The animals were heparinized and the preparation autoperfused (constant pressure). Total tissue volume changes were determined by the volume recorder. Total vascular volume changes were calculated from changes in paw 51Cr-red blood cell radioactivity measured by a scintillation detector. Arterial pressure and paw blood flow were monitored. The tibial and deep fibular nerves were each separately stimulated at 1, 5, and 15 Hz. Deep fibular nerve stimulations resulted in progressively significant increases in precapillary flow resistance. Vascular and tissue volumes decreased with stimulation frequency but vascular volume decreased significantly less than tissue volume change. Tibial nerve stimulation resulted in significant precapillary resistance increases. Vascular and tissue volumes decreased by similar amounts. Thus, deep fibular nerve stimulation causes passive decrease in venous volume, reduced capillary pressure, and fluid absorption. Tibial nerve stimulation causes active arterial and venous constriction maintaining capillary pressure with minimal fluid transfer.
犬后爪血管的神经支配通过胫神经、腓深神经和腓浅神经分别控制串联和并联的血管。后者主要影响静脉。胫神经和腓深神经对静脉的影响尚未得到充分明确。将麻醉犬的右后爪在体积记录器中进行血管和神经隔离。动物进行肝素化处理，制备物进行自身灌注（恒压）。总组织体积变化由体积记录器测定。总血管体积变化通过闪烁探测器测量的爪部51Cr - 红细胞放射性变化来计算。监测动脉血压和爪部血流。分别以1、5和15Hz的频率单独刺激胫神经和腓深神经。腓深神经刺激导致毛细血管前血流阻力逐渐显著增加。血管和组织体积随刺激频率降低，但血管体积减少明显少于组织体积变化。胫神经刺激导致毛细血管前阻力显著增加。血管和组织体积减少量相似。因此，腓深神经刺激导致静脉体积被动减少、毛细血管压力降低和液体吸收。胫神经刺激导致动脉和静脉主动收缩，以最小的液体转移维持毛细血管压力。
