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重新审视影响印度五岁以下儿童死亡率的因素:广义加性 Cox 比例风险模型的应用。

Revisiting Factors Influencing Under-Five Mortality in India: The Application of a Generalised Additive Cox Proportional Hazards Model.

机构信息

Department of Biostatistics, All India Institute of Medical Sciences, New Delhi 110029, India.

出版信息

Int J Environ Res Public Health. 2024 Sep 29;21(10):1303. doi: 10.3390/ijerph21101303.

DOI:10.3390/ijerph21101303
PMID:39457276
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11507100/
Abstract

BACKGROUND

Despite the implementation of various preventive measures, India continues to experience an alarmingly high under-five mortality rate (U5MR). The most recent nationwide data on U5MRs has provided an opportunity to re-examine the associated factors of U5MRs using advanced techniques. This study attempted to identify the associated determinants of U5MRs via the generalised additive Cox proportional hazards method.

METHODS

This study analysed the fifth round of unit-level data for 213,612 children from the National Family Health Survey (NFHS-5) to identify the risk factors associated with U5MRs, employing a generalised additive Cox proportional hazards regression analysis.

RESULTS

The children who had a length of pregnancy of less than 9 months had a 2.621 (95% CI: 2.494, 2.755) times greater hazard of U5MRs than the children who had a gestational period of 9 months or more. The non-linear association with U5MRs was highest in the mother's age, followed by the mother's haemoglobin, the mother's education, and household wealth score. The relationships between the mother's age and the mother's haemoglobin level with the U5MR were found to be U-shaped.

CONCLUSIONS

This study highlights the importance of addressing maternal and socioeconomic factors while improving access to healthcare services in order to reduce U5MRs in India. Furthermore, the findings underscore the necessity for more sophisticated approaches to healthcare delivery that consider the non-linear relationships between predictor variables and U5MRs.

摘要

背景

尽管实施了各种预防措施,印度五岁以下儿童死亡率(U5MR)仍然居高不下。最近的全国性 U5MR 数据提供了一个机会,可以使用先进的技术重新检查 U5MR 的相关因素。本研究试图通过广义加性 Cox 比例风险方法确定 U5MR 的相关决定因素。

方法

本研究分析了来自全国家庭健康调查(NFHS-5)的 213612 名儿童的第五轮单位水平数据,以确定与 U5MR 相关的风险因素,采用广义加性 Cox 比例风险回归分析。

结果

妊娠不足 9 个月的儿童与妊娠 9 个月或以上的儿童相比,U5MR 的危险度高 2.621 倍(95%CI:2.494,2.755)。与 U5MR 的非线性关系以母亲年龄最大,其次是母亲的血红蛋白、母亲的教育程度和家庭财富评分。发现母亲年龄与母亲血红蛋白水平与 U5MR 之间呈 U 形关系。

结论

本研究强调了在改善医疗保健服务的获取的同时,解决母婴和社会经济因素对于降低印度 U5MR 的重要性。此外,研究结果强调了需要更复杂的医疗保健提供方法,考虑预测变量与 U5MR 之间的非线性关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f55/11507100/58a7773d3e58/ijerph-21-01303-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f55/11507100/959d8253642c/ijerph-21-01303-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f55/11507100/58a7773d3e58/ijerph-21-01303-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f55/11507100/959d8253642c/ijerph-21-01303-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f55/11507100/58a7773d3e58/ijerph-21-01303-g003.jpg

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National, regional, and global estimates of preterm birth in 2020, with trends from 2010: a systematic analysis.2020 年全球、区域和国家早产估计数及其 2010 年以来的变化趋势:系统分析。
Lancet. 2023 Oct 7;402(10409):1261-1271. doi: 10.1016/S0140-6736(23)00878-4.
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Household structure, composition and child mortality in the unfolding antiretroviral therapy era in rural South Africa: comparative evidence from population surveillance, 2000-2015.
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Differential impact of maternal education on under-five mortality in rural and urban India.母亲受教育程度对印度城乡 5 岁以下儿童死亡率的影响差异。
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An update on explaining the rural-urban gap in under-five mortality in India.印度五岁以下儿童死亡率城乡差距解释的最新进展。
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