Lee Chao-Lin, Wang Ping-Chen, Chen Yi-Ling, Chen Zen-Yong, Uen Ching-Cherng, Lai Hsien-Yung, Shiao Chih-Chung
Division of Neurology, Department of Internal Medicine, Camillian Saint Mary's Hospital Luodong, No. 160, Zhongzheng S. Rd., Luodong 265, Yilan, Taiwan.
Department of Medical Research and Education, Camillian Saint Mary's Hospital Luodong, No. 160, Zhongzheng S. Rd., Luodong 265, Yilan, Taiwan.
Biomedicines. 2024 Oct 16;12(10):2364. doi: 10.3390/biomedicines12102364.
With the increasing prevalence of end-stage kidney disease, the number of patients requiring hemodialysis (HD) continues to rise. While life-sustaining, HD is often associated with adverse effects such as muscle loss, physical deconditioning, fatigue, and compromised health-related quality of life (HRQoL). Recent research suggests that intradialytic exercise (IDE) and home-based exercise (HBE) may mitigate these adverse effects and improve patient outcomes. However, the existing literature mainly focuses on the outcomes of both exercises, whereas the comparison of types is often omitted. Hence, this review consolidates findings from studies investigating the effectiveness, implementation, safety, feasibility, and adherence of different types of IDE and HBE in HD patients. Overall, the current literature bolsters the significance of IDE and HBE for improving health in HD patients. IDE and HBE enhance physical function, cardiopulmonary capacity, HRQoL, and cognitive well-being. Some research proposed an indirect link between IDE and survival rates. Despite these benefits, challenges remain in implementing these exercise modalities, including patient adherence and the feasibility of routine exercise during HD sessions. Integrating these exercises into routine care allows healthcare providers to enhance outcomes for HD patients. Further research is suggested to optimize exercise protocols and explore long-term effects and cost-effectiveness.
随着终末期肾病患病率的不断上升，需要进行血液透析（HD）的患者数量持续增加。虽然血液透析维持了生命，但它常常伴随着一些不良反应，如肌肉流失、身体机能下降、疲劳以及健康相关生活质量（HRQoL）受损。最近的研究表明，透析期间运动（IDE）和居家运动（HBE）可能会减轻这些不良反应并改善患者预后。然而，现有文献主要关注这两种运动的结果，而对运动类型的比较往往被忽略。因此，本综述整合了研究不同类型的透析期间运动和居家运动在血液透析患者中的有效性、实施情况、安全性、可行性和依从性的研究结果。总体而言，当前文献支持透析期间运动和居家运动对改善血液透析患者健康的重要性。透析期间运动和居家运动可增强身体功能、心肺能力、健康相关生活质量和认知幸福感。一些研究提出了透析期间运动与生存率之间的间接联系。尽管有这些益处，但在实施这些运动方式方面仍存在挑战，包括患者的依从性以及在血液透析过程中进行常规运动的可行性。将这些运动纳入常规护理可使医疗保健提供者提高血液透析患者的预后。建议进一步开展研究以优化运动方案，并探索长期效果和成本效益。
