Agamanolis D P, Hite S H, Platt M S, Boeckman C R
Surg Neurol. 1986 Mar;25(3):261-6. doi: 10.1016/0090-3019(86)90236-3.
Four patients with the Arnold-Chiari malformation had massive prenatal contamination of the spinal cord and brainstem (and also of the cerebral ventricles in one case) by amniotic squamous cells and lanugo hair, which had entered through open meningomyeloceles. Amniotic contents were present in the subarachnoid space, central canal, fourth ventricle, and aqueduct and were also embedded in neural tissue, causing severe gliosis, fibrosis, and blockage. The mechanism of the complication and its implications in the prognosis of patients with the Arnold-Chiari malformation are discussed.
4例患有阿诺德-奇阿利畸形的患者，其脊髓和脑干（其中1例还包括脑室）在产前受到羊膜鳞状细胞和胎毛的大量污染，这些物质通过开放性脊柱裂进入。蛛网膜下腔、中央管、第四脑室和导水管中均有羊水成分，并且还嵌入神经组织，导致严重的胶质增生、纤维化和梗阻。本文讨论了该并发症的机制及其对阿诺德-奇阿利畸形患者预后的影响。
