School of Electronic and Information Engineering, China West Normal University, Nanchong 637000, China.
Molecules. 2024 Oct 16;29(20):4898. doi: 10.3390/molecules29204898.
At present, the effects of environmental electromagnetic irradiation on the metabolism of organisms have attracted extensive attention, but the mechanism is still not clear. D-glucose plays an important role in the metabolism of organisms. In this work, the change in the optical rotation of D-glucose solution under an electrostatic field is measured experimentally, so as to explain the mechanism of the electric field-induced biological effect. The experimental results show that the electrostatic field can alter the optical rotation of D-glucose solution at different temperatures. Under the different strengths of electrostatic field, the specific rotation of D-glucose solution increases at different temperatures; the maximum increase can reach 2.07%, but the effect of temperature and electric field strength on the rotation increment is nonlinear and very complex. Further, it turns out that the proportion of α-D-glucose in solution increases by up to 3.25% under the electrostatic field, while the proportion of β-D-glucose decreases by as much as 1.75%. The experimental study confirms that electrostatic field can change the proportion of two conformation molecules (α and β-D-glucose) in D-glucose solution, which can provide a novel explanation for the mechanism of the electric field-induced biological effect.
目前，环境电磁辐射对生物体代谢的影响引起了广泛关注，但机制尚不清楚。D-葡萄糖在生物体代谢中起着重要作用。在这项工作中，通过实验测量了 D-葡萄糖溶液在静电场下的旋光度变化，从而解释电场诱导生物效应的机制。实验结果表明，静电场可以在不同温度下改变 D-葡萄糖溶液的旋光度。在不同强度的静电场下，D-葡萄糖溶液的比旋光度在不同温度下增加；最大增加可达 2.07%，但温度和电场强度对旋转增量的影响是非线性的，非常复杂。进一步研究表明，在静电场下，溶液中α-D-葡萄糖的比例最多增加了 3.25%，而β-D-葡萄糖的比例最多减少了 1.75%。实验研究证实，静电场可以改变 D-葡萄糖溶液中两种构象分子（α和β-D-葡萄糖）的比例，为电场诱导生物效应的机制提供了新的解释。
